Hidehiro Toh
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Explore the profile of Hidehiro Toh including associated specialties, affiliations and a list of published articles.
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78
Citations
4288
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Recent Articles
1.
Toh H, Okae H, Shirane K, Sato T, Hamada H, Kikutake C, et al.
BMC Genomics
. 2024 Nov;
25(1):1050.
PMID: 39506688
Background: The placenta is essential for nutrient exchange and hormone production between the mother and the developing fetus and serves as an invaluable model for epigenetic research. Most epigenetic studies...
2.
Hasiqimuge , Hano C, Arakawa K, Yoshida S, Zhao J, Toh H, et al.
Microorganisms
. 2024 Sep;
12(9).
PMID: 39338456
Bacteriocins produced by lactic acid bacteria are known to be useful tools for food biopreservation and fermentation control. subsp. 406 and 213M0 isolated from different samples of Mongolian traditional fermented...
3.
Kubota K, Oishi M, Taniguchi E, Akazawa A, Matsui K, Kitazaki K, et al.
PLoS One
. 2024 Sep;
19(9):e0308551.
PMID: 39331563
Cytoplasmic male sterility (CMS) is a mitochondrial-encoded trait that confers reproductive defects in males but not in females or any vegetative function. Why CMS is so often found in plants...
4.
Toh H, Sasaki H
Life Sci Alliance
. 2024 Jan;
7(4).
PMID: 38233073
DNA methylation is an essential epigenetic mechanism that regulates cellular reprogramming and development. Studies using whole-genome bisulfite sequencing have revealed distinct DNA methylome landscapes in human and mouse cells and...
5.
Uehara R, Au Yeung W, Toriyama K, Ohishi H, Kubo N, Toh H, et al.
PLoS Genet
. 2023 Aug;
19(8):e1010855.
PMID: 37527244
Establishment of a proper DNA methylation landscape in mammalian oocytes is important for maternal imprinting and embryonic development. De novo DNA methylation in oocytes is mediated by the DNA methyltransferase...
6.
Tamakoshi M, Hijikata A, Yura K, Oshima K, Toh H, Mitsuoka K, et al.
J Gen Appl Microbiol
. 2023 Jul;
69(2):117-124.
PMID: 37423744
A Thermus thermophilus lytic phage was isolated from a Japanese hot spring using a type IV pili-deficient strain as an indicator host, and designated as φMN1. Electron microscopic (EM) examination...
7.
Maruyama O, Li Y, Narita H, Toh H, Au Yeung W, Sasaki H
BMC Bioinformatics
. 2022 Sep;
23(1):371.
PMID: 36096737
Background: Epigenetic modifications established in mammalian gametes are largely reprogrammed during early development, however, are partly inherited by the embryo to support its development. In this study, we examine CpG...
8.
Kibe K, Shirane K, Ohishi H, Uemura S, Toh H, Sasaki H
PLoS Genet
. 2021 May;
17(5):e1009570.
PMID: 34048432
DNA methylation at CG sites is important for gene regulation and embryonic development. In mouse oocytes, de novo CG methylation requires preceding transcription-coupled histone mark H3K36me3 and is mediated by...
9.
Hiramoto T, Tahara M, Liao J, Soda Y, Miura Y, Kurita R, et al.
Mol Ther
. 2019 Nov;
28(1):129-141.
PMID: 31677955
Recent advances in gene therapy technologies have enabled the treatment of congenital disorders and cancers and facilitated the development of innovative methods, including induced pluripotent stem cell (iPSC) production and...
10.
Yamanaka S, Nishihara H, Toh H, Nagai L, Hashimoto K, Park S, et al.
Dev Cell
. 2019 Sep;
51(1):21-34.e5.
PMID: 31474564
Facultative heterochromatin forms and reorganizes in response to external stimuli. However, how the initial establishment of such a chromatin state is regulated in cell-cycle-arrested cells remains unexplored. Mouse gonocytes are...