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Heyang Zhang

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Articles 89
Citations 403
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Recent Articles
1.
Zhang H, Barz M
J Control Release . 2025 Mar; 381:113559. PMID: 40023226
Lipid nanoparticles (LNPs) are the most established and clinically advanced platform for RNA delivery. While significant efforts have been made to improve RNA delivery efficiency for improved protein production, the...
2.
Ma X, Cong R, Cui X, Tang Y, Ren J, Hou J, et al.
J Control Release . 2025 Feb; 381:113581. PMID: 40020928
Psoriasis is a prevalent chronic inflammatory skin disease characterized by immune cell activation and aberrant keratinocyte proliferation. Signal transducer and activator of transcription 3 (STAT3) plays a key role in...
3.
Wan S, Xia X, Gao Y, Zhang H, Zhang Z, Wu F, et al.
Science . 2025 Feb; 387(6737):978-984. PMID: 40014713
Shape-anisotropic nanocrystals and patchy particles have been explored to construct complex superstructures, but most studies have focused on convex shapes. We report that nonconvex, dumbbell-shaped nanocrystals (nanodumbbells) exhibit globally interlocking...
4.
Wang S, Jiang D, Xiao Y, Qin Q, Zhang H, Ye L, et al.
Adv Sci (Weinh) . 2025 Feb; :e2414230. PMID: 39951008
The 3D human pituitary organoid represents a promising laboratory model for investigating human pituitary diseases. Nonetheless, this technology is still in its nascent stage, with uncertainties regarding the cellular composition,...
5.
Wei L, Liu C, Wang S, Zhang H, Ruan G, Xie H, et al.
Nutrition . 2025 Feb; 132:112690. PMID: 39938385
Objectives: This study investigated the correlation between body mass index (BMI), bioelectrical impedance analysis (BIA)-derived specific body compositions, and the obesity paradox, with a focus on sex differences in non-smallcell...
6.
Xie H, Wei L, Ruan G, Zhang H, Shi H
J Inflamm Res . 2025 Jan; 18():573-587. PMID: 39831196
Purpose: Interleukin-6 (IL-6) is a central factor linking inflammation to cancer. This study aimed to provide a comprehensive assessment of the prognostic value of IL-6 and its immunotherapeutic features using...
7.
Shi J, Liu C, Zheng X, Chen Y, Zhang H, Liu T, et al.
Sci Rep . 2025 Jan; 15(1):1322. PMID: 39779840
Cancer is a fatal disease with a high global prevalence and is associated with an increased incidence of metabolic disorders. This study aimed to develop a novel metabolic prognostic system...
8.
Liu C, Deng L, Lin S, Liu T, Ren J, Shi J, et al.
Support Care Cancer . 2024 Dec; 33(1):50. PMID: 39710757
Background: Enteral nutrition (EN) is commonly used for nutritional support in patients with cancer. Whether inflammation, one of the driving factors of malnutrition and cancer, affects the association between EN...
9.
Qin Q, Ruan H, Zhang H, Xu Z, Pan W, Yan X, et al.
Int J Mol Sci . 2024 Dec; 25(23). PMID: 39684760
MYSM1, a deubiquitinating enzyme, plays a pivotal role in diverse biological processes. Both MYSM1 knockout mice and patients with Mysm1 gene mutations exhibit developmental abnormalities across multiple tissues and organs....
10.
Li H, Zhou Z, Ma T, Wang K, Zhang H, Alawadhi A, et al.
J Am Chem Soc . 2024 Dec; 146(51):35486-35492. PMID: 39679572
We have developed a polyethylenimine-functionalized covalent organic framework (COF) for capturing CO from the air. It was synthesized by the crystallization of an imine-linked COF, termed imine-COF-709, followed by linkage...