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Hetty C M Sips

Explore the profile of Hetty C M Sips including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 301
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Recent Articles
1.
Amaya J, Sips H, Viho E, Kroon J, Meijer O
Front Endocrinol (Lausanne) . 2024 Feb; 14:1292024. PMID: 38303978
Glucocorticoids are key executors of the physiological response to stress. Previous studies in mice showed that the androgen receptor (AR) influenced the transcriptional outcome of glucocorticoid treatment in white and...
2.
In Het Panhuis W, Schonke M, Siebeler R, Banen D, Pronk A, Streefland T, et al.
FASEB J . 2023 Jan; 37(2):e22772. PMID: 36645117
Circadian disruption (CD) is the consequence of a mismatch between endogenous circadian rhythms and behavior, and frequently occurs in shift workers. CD has often been linked to impairment of glucose...
3.
In Het Panhuis W, Schonke M, Siebeler R, Afkir S, Baelde R, Pronk A, et al.
Aging (Albany NY) . 2022 Oct; 14(19):7734-7751. PMID: 36202134
Brown adipose tissue (BAT) contributes to cardiometabolic health by taking up glucose and lipids for oxidation, a process that displays a strong diurnal rhythm. While aging has been shown to...
4.
van Eenige R, In Het Panhuis W, Schonke M, Jouffe C, Devilee T, Siebeler R, et al.
Mol Metab . 2022 Apr; 60:101497. PMID: 35413480
Objective: Brown adipose tissue (BAT) burns fatty acids (FAs) to produce heat, and shows diurnal oscillation in glucose and triglyceride (TG)-derived FA-uptake, peaking around wakening. Here we aimed to gain...
5.
Amaya J, Viho E, Sips H, Lalai R, Sahut-Barnola I, Dumontet T, et al.
J Neuroendocrinol . 2022 Apr; 34(4):e13125. PMID: 35365898
Excess glucocorticoid exposure affects emotional and cognitive brain functions. The extreme form, Cushing's syndrome, is adequately modelled in the AdKO mouse, consequential to adrenocortical hypertrophy and hypercorticosteronemia. We previously reported...
6.
In Het Panhuis W, Tsaalbi-Shtylik A, Schonke M, van Harmelen V, Pronk A, Streefland T, et al.
Am J Physiol Endocrinol Metab . 2022 Feb; 322(3):E319-E329. PMID: 35156394
DNA damage responses compete for cellular resources with metabolic pathways, but little is known about the metabolic consequences of impaired DNA replication, a process called replication stress. Here we characterized...
7.
Brinks J, van Dijk E, Kielbasa S, Mei H, van der Veen I, Peters H, et al.
J Clin Endocrinol Metab . 2021 Sep; 107(2):512-524. PMID: 34546342
Context: Central serous chorioretinopathy (CSC) is a severe ocular disease characterized by fluid accumulation under the retina and abnormalities in the underlying vascular layer, the choroid. CSC has a striking...
8.
Florijn B, Duijs J, Klaver M, Kuipers E, Kooijman S, Prins J, et al.
Eur J Endocrinol . 2021 Aug; 185(4):539-552. PMID: 34342596
Objective: Sex steroid hormones like estrogens have a key role in the regulation of energy homeostasis and metabolism. In transwomen, gender-affirming hormone therapy like estradiol (in combination with antiandrogenic compounds)...
9.
Liu J, Kuipers E, Sips H, Dorleijn J, van Dam A, Christodoulides C, et al.
Biochim Biophys Acta Mol Cell Biol Lipids . 2019 Aug; 1864(12):158511. PMID: 31465889
Brown adipose tissue (BAT) is a potential target to treat cardiometabolic disorders because of its capacity to combust glucose and fatty acids for thermoregulation. Its cellular and molecular investigation in...
10.
van Weert L, Buurstede J, Sips H, Vettorazzi S, Mol I, Hartmann J, et al.
J Neuroendocrinol . 2019 May; 31(8):e12735. PMID: 31121060
Brain mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) respond to the same glucocorticoid hormones but can have differential effects on cellular function. Several lines of evidence suggest that MR-specific target...