Hesham ElAbd
Overview
Explore the profile of Hesham ElAbd including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
1207
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0
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Recent Articles
1.
Mayr G, Bublitz M, Steiert T, Loscher B, Wittig M, ElAbd H, et al.
Front Immunol
. 2024 Dec;
15:1452637.
PMID: 39726599
Kell is one of the most complex blood group systems, with a highly polymorphic genetic background. Extensive allelic variations in the gene affect the encoded erythrocyte surface protein Kell. Genetic...
2.
Mahdy A, Lokes E, Schopfel V, Kriukova V, Britanova O, Steiert T, et al.
J Autoimmun
. 2024 Nov;
149():103337.
PMID: 39571301
Multiple alterations in the T cell repertoire were identified in many chronic inflammatory diseases such as inflammatory bowel disease, multiple sclerosis, and rheumatoid arthritis, suggesting that T cells might, directly...
3.
ElAbd H, Franke A
Methods Mol Biol
. 2024 Mar;
2758:425-443.
PMID: 38549028
Human leukocyte antigen (HLA) proteins are a group of glycoproteins that are expressed at the cell surface, where they present peptides to T cells through physical interactions with T-cell receptors...
4.
ElAbd H, Bacher P, Tholey A, Lenz T, Franke A
Front Immunol
. 2023 Apr;
14:1107266.
PMID: 37063883
The human leukocyte antigen (HLA) proteins are an indispensable component of adaptive immunity because of their role in presenting self and foreign peptides to T cells. Further, many complex diseases...
5.
Steiert T, Fuss J, Juzenas S, Wittig M, Hoeppner M, Vollstedt M, et al.
NAR Genom Bioinform
. 2022 Jul;
4(3):lqac051.
PMID: 35855323
Hybridisation-based targeted enrichment is a widely used and well-established technique in high-throughput second-generation short-read sequencing. Despite the high potential to genetically resolve highly repetitive and variable genomic sequences by, for...
6.
Degenhardt F, Ellinghaus D, Juzenas S, Lerga-Jaso J, Wendorff M, Maya-Miles D, et al.
Hum Mol Genet
. 2022 Jul;
31(23):3945-3966.
PMID: 35848942
Given the highly variable clinical phenotype of Coronavirus disease 2019 (COVID-19), a deeper analysis of the host genetic contribution to severe COVID-19 is important to improve our understanding of underlying...
7.
ElAbd H, Degenhardt F, Koudelka T, Kamps A, Tholey A, Bacher P, et al.
BMC Bioinformatics
. 2021 Aug;
22(1):405.
PMID: 34404349
Background: The human leukocyte antigen (HLA) proteins play a fundamental role in the adaptive immune system as they present peptides to T cells. Mass-spectrometry-based immunopeptidomics is a promising and powerful...
8.
Degenhardt F, Mayr G, Wendorff M, Boucher G, Ellinghaus E, Ellinghaus D, et al.
Hum Mol Genet
. 2021 Feb;
30(5):356-369.
PMID: 33555323
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gut. Genetic association studies have identified the highly variable human leukocyte antigen (HLA) region as the strongest susceptibility locus...
9.
Wendorff M, Garcia Alvarez H, Osterbye T, ElAbd H, Rosati E, Degenhardt F, et al.
Front Immunol
. 2020 Sep;
11:1705.
PMID: 32903714
Human Leukocyte Antigen class II (HLA-II) molecules present peptides to T lymphocytes and play an important role in adaptive immune responses. Characterizing the binding specificity of single HLA-II molecules has...
10.
Ellinghaus D, Degenhardt F, Bujanda L, Buti M, Albillos A, Invernizzi P, et al.
N Engl J Med
. 2020 Jun;
383(16):1522-1534.
PMID: 32558485
Background: There is considerable variation in disease behavior among patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19). Genomewide association analysis...