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Herve Tettelin

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Articles 124
Citations 9212
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Recent Articles
1.
Kilian M, Slotved H, Fuursted K, DMello A, Tettelin H
Int J Syst Evol Microbiol . 2025 Mar; 75(3). PMID: 40067351
The commensal species and are genetically diverse to a degree that challenges traditional definitions of species. This causes automatic identification based on DNA sequences or cellular extract profiles problematic. Based...
2.
Olivella-Gomez J, Lozada J, Serrano-Mayorga C, Mendez-Castillo L, Acosta-Gonzalez A, Vinan Garces A, et al.
PLoS One . 2025 Feb; 20(2):e0318320. PMID: 39937814
Purpose: Streptococcus pneumoniae (Spn) is the primary bacterial cause of lower respiratory tract infections (LRTI) globally, particularly impacting older adults and children. While Spn colonization in children is linked to...
3.
Dai Y, Edwards V, Yu Q, Tettelin H, Stein D, Song W
J Clin Invest . 2024 Nov; 135(2. PMID: 39585777
Gonorrhea, caused by the human-restricted pathogen Neisseria gonorrhoeae, is a commonly reported sexually transmitted infection. Since most infections in women are asymptomatic, the true number of infections is likely much...
4.
Melendez J, Edwards V, Muniz Tirado A, Hardick J, Mehta A, Aluvathingal J, et al.
Antimicrob Agents Chemother . 2024 Oct; 68(12):e0092724. PMID: 39445818
Antimicrobial resistance in (Ng) has severely reduced treatment options, including azithromycin (AZM), which had previously been recommended as dual therapy with ceftriaxone. This study characterizes the emergence of high-level resistance...
5.
Le Run E, Tettelin H, Holland S, Zelazny A
Antimicrob Agents Chemother . 2024 Sep; 68(10):e0067324. PMID: 39254295
Treatment of pulmonary disease requires multiple antibiotics including intravenous β-lactams (e.g., imipenem). produces a β-lactamase (Bla) that inactivates β-lactam drugs but less efficiently carbapenems. Due to intrinsic and acquired resistance...
6.
Chembilikandy V, DMello A, Tettelin H, Martinez E, Orihuela C
Appl Environ Microbiol . 2024 Aug; 90(9):e0101024. PMID: 39140740
Importance: We introduce a new strategy aimed at streamlining the process for marker-less allelic replacement in , a Gram-positive bacterium and leading cause of pneumonia, meningitis, and ear infections. Our...
7.
Potter A, Edwards V, DMello A, Gray M, Shetty A, Forehand A, et al.
PLoS Pathog . 2024 Jul; 20(7):e1012369. PMID: 38976720
Neisseria gonorrhoeae (the gonococcus, Gc) causes the sexually transmitted infection gonorrhea. Gc is a prominent threat to human health by causing severe lifelong sequelae, including infertility and chronic pelvic pain,...
8.
Le Run E, Tettelin H, Holland S, Zelazny A
bioRxiv . 2024 Jun; PMID: 38903073
Treatment of pulmonary disease requires multiple antibiotics including intravenous β-lactams (e.g., imipenem, meropenem). produces a β-lactamase (Bla) that inactivates β-lactam drugs but less efficiently carbapenems. Due to intrinsic and acquired...
9.
Alles M, Gunasena M, Zia T, DMello A, Bhattarai S, Mulhern W, et al.
Infect Immun . 2024 May; 92(7):e0004824. PMID: 38814083
Commensal bacteria are crucial in maintaining host physiological homeostasis, immune system development, and protection against pathogens. Despite their significance, the factors influencing persistent bacterial colonization and their impact on the...
10.
Bessen D, Beall B, Hayes A, Huang W, DiChiara J, Velusamy S, et al.
mBio . 2024 Apr; 15(5):e0069324. PMID: 38587426
Among genes present in all group A streptococci (GAS), those encoding M-fibril and T-pilus proteins display the highest levels of sequence diversity, giving rise to the two primary serological typing...