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Herbert Braselmann

Explore the profile of Herbert Braselmann including associated specialties, affiliations and a list of published articles. Areas
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Articles 43
Citations 796
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Recent Articles
1.
Selmansberger M, Michna A, Braselmann H, Hofig I, Schorpp K, Weber P, et al.
Radiat Oncol . 2020 Jul; 15(1):182. PMID: 32727620
Background: We present a functional gene association network of the CLIP2 gene, generated by de-novo reconstruction from transcriptomic microarray data. CLIP2 was previously identified as a potential marker for radiation...
2.
Samaga D, Hornung R, Braselmann H, Hess J, Zitzelsberger H, Belka C, et al.
Radiat Oncol . 2020 May; 15(1):109. PMID: 32410693
Background: Prognostic models based on high-dimensional omics data generated from clinical patient samples, such as tumor tissues or biopsies, are increasingly used for prognosis of radio-therapeutic success. The model development...
3.
Abend M, Pfeiffer R, Port M, Hatch M, Bogdanova T, Tronko M, et al.
Int J Radiat Biol . 2020 Apr; 97(1):12-18. PMID: 32310011
Purpose: We herein report on changes in gene expression after radiation exposure to iodine-131 from the Chernobyl accident in the Ukrainian-American thyroid cohort and to external gamma ray or internal...
4.
Liu X, Li J, Cadilha B, Markota A, Voigt C, Huang Z, et al.
Sci Adv . 2019 Jun; 5(6):eaav4275. PMID: 31223646
Carcinoma cells undergo epithelial-mesenchymal transition (EMT); however, contributions of EMT heterogeneity to disease progression remain a matter of debate. Here, we addressed the EMT status of ex vivo cultured circulating...
5.
Hess J, Unger K, Maihoefer C, Schuttrumpf L, Wintergerst L, Heider T, et al.
Clin Cancer Res . 2018 Sep; 25(5):1505-1516. PMID: 30171046
Purpose: Human papillomavirus (HPV)-negative head and neck squamous cell carcinoma (HNSCC) is associated with unfavorable prognosis, while independent prognostic markers remain to be defined. Experimental Design: We retrospectively performed miRNA...
6.
Caldwell R, Braselmann H, Heuer S, Schotz U, Zitzelsberger H
Immunol Cell Biol . 2018 Apr; 96(9):948-957. PMID: 29665088
Activation-induced cytidine deaminase (AID) is required for the immunoglobulin diversification processes of somatic hypermutation, gene conversion and class-switch recombination. The targeting of AID's deamination activity is thought to be a...
7.
Wilke C, Braselmann H, Hess J, Klymenko S, Chumak V, Zakhartseva L, et al.
Int J Cancer . 2018 Apr; 143(6):1505-1515. PMID: 29663366
Breast cancer is the second leading cause of cancer death among women worldwide and besides life style, age and genetic risk factors, exposure to ionizing radiation is known to increase...
8.
Dalke C, Neff F, Kaur Bains S, Bright S, Lord D, Reitmeir P, et al.
Radiat Environ Biophys . 2018 Jan; 57(2):99-113. PMID: 29327260
Because of the increasing application of ionizing radiation in medicine, quantitative data on effects of low-dose radiation are needed to optimize radiation protection, particularly with respect to cataract development. Using...
9.
Wilke C, Hess J, Klymenko S, Chumak V, Zakhartseva L, Bakhanova E, et al.
Int J Cancer . 2017 Sep; 142(3):573-583. PMID: 28944451
Ionizing radiation is a well-recognized risk factor for the development of breast cancer. However, it is unknown whether radiation-specific molecular oncogenic mechanisms exist. We investigated post-Chernobyl breast cancers from radiation-exposed...
10.
Hess J, Unger K, Orth M, Schotz U, Schuttrumpf L, Zangen V, et al.
Cancer Lett . 2016 Nov; 386:87-99. PMID: 27867017
Radio (chemo) therapy is a crucial treatment modality for head and neck squamous cell carcinoma (HNSCC), but relapse is frequent, and the underlying mechanisms remain largely elusive. Therefore, novel biomarkers...