Henri-Alexandre Michaud
Overview
Explore the profile of Henri-Alexandre Michaud including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
691
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Recent Articles
1.
Di Michele M, Attina A, Roux P, Tabet I, Laguesse S, Florido J, et al.
Nat Commun
. 2025 Jan;
16(1):67.
PMID: 39747033
Pyruvate metabolism defects lead to severe neuropathies such as the Leigh syndrome (LS) but the molecular mechanisms underlying neuronal cell death remain poorly understood. Here, we unravel a connection between...
2.
Bruciamacchie M, Garambois V, Vie N, Bessede T, Michaud H, Chepeaux L, et al.
Br J Cancer
. 2024 Nov;
132(2):222-235.
PMID: 39613844
Background: In pancreatic ductal adenocarcinoma (PDAC), the dense stroma rich in cancer-associated fibroblasts (CAFs) and the immunosuppressive microenvironment confer resistance to treatments. To overcome such resistance, we tested the combination...
3.
Thibaudin M, Fumet J, Chibaudel B, Bennouna J, Borg C, Martin-Babau J, et al.
Nat Med
. 2023 Aug;
29(8):2087-2098.
PMID: 37563240
Although patients with microsatellite instable metastatic colorectal cancer (CRC) benefit from immune checkpoint blockade, chemotherapy with targeted therapies remains the only therapeutic option for microsatellite stable (MSS) tumors. The single-arm,...
4.
Alaoui L, Villar J, Leclere R, Le Gallou S, Relouzat F, Michaud H, et al.
J Exp Med
. 2023 Apr;
220(7).
PMID: 37036425
Macrophages play a central role in tissue homeostasis and host defense. However, the properties of human macrophages in non-diseased tissues remain poorly understood. Here, we characterized human tonsil macrophages and...
5.
Glasson Y, Chepeaux L, Dume A, Jay P, Pirot N, Bonnefoy N, et al.
Front Immunol
. 2023 Feb;
13:1011617.
PMID: 36741363
Currently, the study of resistance mechanisms and disease progression in cancer relies on the capacity to analyze tumors as a complex ecosystem of healthy and malignant cells. Therefore, one of...
6.
Glasson Y, Chepeaux L, Dume A, Lafont V, Faget J, Bonnefoy N, et al.
Semin Immunopathol
. 2023 Jan;
45(1):17-28.
PMID: 36598557
Solid tumors have a dynamic ecosystem in which malignant and non-malignant (endothelial, stromal, and immune) cell types constantly interact. Importantly, the abundance, localization, and functional orientation of each cell component...
7.
Robert M, Chepeaux L, Glasson Y, Dume A, Sannier A, Papo T, et al.
Autoimmun Rev
. 2022 Oct;
22(1):103216.
PMID: 36280094
No abstract available.
8.
Chabab G, Barjon C, Abdellaoui N, Salvador-Prince L, Dejou C, Michaud H, et al.
J Leukoc Biol
. 2020 May;
107(6):1057-1067.
PMID: 32362028
γδ T cells contribute to the immune response against many cancers, notably through their powerful effector functions that lead to the elimination of tumor cells and the recruitment of other...
9.
Bourillon L, Demontoy S, Lenglet A, Zampieri A, Fraisse J, Jarlier M, et al.
Int J Radiat Oncol Biol Phys
. 2020 Jan;
106(5):1039-1051.
PMID: 31959545
Purpose: The outcome of locally advanced cervical cancer (LACC) is dismal. Biomarkers are needed to individualize treatments and to improve patient outcomes. Here, we investigated whether coexpression of epidermal growth...
10.
Perrot I, Michaud H, Giraudon-Paoli M, Augier S, Docquier A, Gros L, et al.
Cell Rep
. 2019 May;
27(8):2411-2425.e9.
PMID: 31116985
Immune checkpoint inhibitors have revolutionized cancer treatment. However, many cancers are resistant to ICIs, and the targeting of additional inhibitory signals is crucial for limiting tumor evasion. The production of...