Henning Arlt
Overview
Explore the profile of Henning Arlt including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
17
Citations
474
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Walther T, Kim S, Arlt H, Voth G, Farese Jr R
Curr Opin Struct Biol
. 2023 May;
80:102606.
PMID: 37150040
Cells store lipids as a reservoir of metabolic energy and membrane component precursors in organelles called lipid droplets (LDs). LD formation occurs in the endoplasmic reticulum (ER) at LD assembly...
2.
Arlt H, Raman B, Filali-Mouncef Y, Hu Y, Leytens A, Hardenberg R, et al.
J Biol Chem
. 2023 Apr;
299(5):104712.
PMID: 37060997
Autophagy is a key process in eukaryotes to maintain cellular homeostasis by delivering cellular components to lysosomes/vacuoles for degradation and reuse of the resulting metabolites. Membrane rearrangements and trafficking events...
3.
Kim S, Chung J, Arlt H, Pak A, Farese Jnr R, Walther T, et al.
Elife
. 2022 May;
11.
PMID: 35583926
Lipid droplets (LDs) are organelles formed in the endoplasmic reticulum (ER) to store triacylglycerol (TG) and sterol esters. The ER protein seipin is key for LD biogenesis. Seipin forms a...
4.
Arlt H, Sui X, Folger B, Adams C, Chen X, Remme R, et al.
Nat Struct Mol Biol
. 2022 Feb;
29(3):194-202.
PMID: 35210614
Lipid droplets (LDs) form in the endoplasmic reticulum by phase separation of neutral lipids. This process is facilitated by the seipin protein complex, which consists of a ring of seipin...
5.
Christiano R, Arlt H, Kabatnik S, Mejhert N, Lai Z, Farese Jr R, et al.
Cell Rep
. 2020 Nov;
33(6):108378.
PMID: 33176155
Protein degradation is mediated by an expansive and complex network of protein modification and degradation enzymes. Matching degradation enzymes with their targets and determining globally which proteins are degraded by...
6.
Sui X, Arlt H, Brock K, Lai Z, DiMaio F, Marks D, et al.
J Cell Biol
. 2018 Oct;
217(12):4080-4091.
PMID: 30327422
Metabolic energy is stored in cells primarily as triacylglycerols in lipid droplets (LDs), and LD dysregulation leads to metabolic diseases. The formation of monolayer-bound LDs from the endoplasmic reticulum (ER)...
7.
Jayson C, Arlt H, Fischer A, Lai Z, Farese Jr R, Walther T
Mol Biol Cell
. 2018 Jun;
29(17):2045-2054.
PMID: 29949452
Rab GTPases recruit peripheral membrane proteins and can define organelle identity. Rab18 localizes to the endoplasmic reticulum (ER) but also to lipid droplets (LDs), where it has been implicated in...
8.
Purushothaman L, Arlt H, Kuhlee A, Raunser S, Ungermann C
Mol Biol Cell
. 2017 Jan;
28(6):783-791.
PMID: 28100638
Endosomes are the major protein-sorting hubs of the endocytic pathway. They sort proteins destined for degradation into internal vesicles while in parallel recycling receptors via tubular carriers back to the...
9.
Kock C, Arlt H, Ungermann C, Heinisch J
Cell Microbiol
. 2016 Jun;
18(9):1251-67.
PMID: 27337501
The cell wall integrity (CWI) pathway of the yeast Saccharomyces cerevisiae relies on the detection of cell surface stress by five sensors (Wsc1, Wsc2, Wsc3, Mid2, Mtl1). Each sensor contains...
10.
Numrich J, Peli-Gulli M, Arlt H, Sardu A, Griffith J, Levine T, et al.
J Cell Sci
. 2015 May;
128(13):2278-92.
PMID: 25999476
Membrane fusion at the vacuole depends on a conserved machinery that includes SNAREs, the Rab7 homolog Ypt7 and its effector HOPS. Here, we demonstrate that Ypt7 has an unexpected additional...