Helga Lorenz
Overview
Explore the profile of Helga Lorenz including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
603
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0
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Recent Articles
1.
Reiber M, Stirling H, Ahuis T, Arias W, Aulehner K, Dressler U, et al.
Br J Pharmacol
. 2024 Oct;
182(3):530-545.
PMID: 39389585
Background And Purpose: Irwin tests are key preclinical study elements for characterising drug-induced neurological side effects. This multicentre study aimed to assess the robustness of Irwin tests across multinational sites...
2.
Morgan S, Besenhofer L, Buck W, Lorenz H, Rhodes J, Yang Y
Toxicol Pathol
. 2016 Sep;
45(1):84-89.
PMID: 27651421
A cutaneous response (localized swelling and/or erythema of the skin) has been noted in dog toxicology studies in which multiple, unrelated compounds were administered orally with copovidone as a vehicle....
3.
Boser P, Mordashova Y, Maasland M, Trommer I, Lorenz H, Hafner M, et al.
Toxicol Pathol
. 2016 Feb;
44(2):259-66.
PMID: 26839325
Hepcidin was originally detected as a liver peptide with antimicrobial activity and it functions as a central regulator in the systemic iron metabolism. Consequently suppression of hepcidin leads to iron...
4.
Backes K, Lorenz H, Laplanche L, Hudzik T, Potschka H, Hempel K
Toxicol Lett
. 2016 Jan;
243:78-87.
PMID: 26732424
Selection of the appropriate non-rodent species in preclinical programs is crucial for good translatability and human safety. There is no data available in the literature which provides exact comparison of...
5.
Sewell F, Chapman K, Baldrick P, Brewster D, Broadmeadow A, Brown P, et al.
Regul Toxicol Pharmacol
. 2014 Aug;
70(1):413-29.
PMID: 25078890
An international expert group which includes 30 organisations (pharmaceutical companies, contract research organisations, academic institutions and regulatory bodies) has shared data on the use of recovery animals in the assessment...
6.
Geiger F, Beverungen M, Lorenz H, Wieland J, Fehr M, Kasten P
J Funct Biomater
. 2014 Jun;
3(2):313-26.
PMID: 24955534
VEGF (vascular endothelial growth factor) promotes vascularization and remodeling of bone substitutes. The aim of this study was to examine the effect of distinct resorbable ceramic carriers on bone forming...
7.
Helbig L, Simank H, Lorenz H, Putz C, Wolfl C, Suda A, et al.
Int Orthop
. 2013 Oct;
38(4):891-7.
PMID: 24170130
Purpose: The increase in methicillin-resistant Staphylococcus aureus (MRSA) infections is currently a major health care problem. Vancomycin is still often the first-line anti-microbiological agent for treating such infections; however, a...
8.
Enright B, Tornesi B, Lorenz H, Whitney K
Birth Defects Res B Dev Reprod Toxicol
. 2013 Jan;
98(1):35-40.
PMID: 23348848
Background: This study was conducted as part of an ILSI-HESIconsortium effort to assess the utility of circulating inhibin B as an early biomarker of testicular toxicity in rats. Methods: Two...
9.
Schroeder K, Simank H, Lorenz H, Swoboda S, Geiss H, Helbig L
J Orthop Res
. 2011 Aug;
30(2):190-5.
PMID: 21815204
The increasing prevalence of methicillin-resistant Staphylococcus aureus (MRSA) infections represents a significant healthcare burden. Vancomycin and linezolid exhibit potent clinical and microbiological activity in MRSA infections. Our purpose was to...
10.
Omlor G, Nerlich A, Wilke H, Pfeiffer M, Lorenz H, Schaaf-Keim M, et al.
Spine (Phila Pa 1976)
. 2009 Nov;
34(25):2730-9.
PMID: 19940730
Study Design: In vivo animal study. Objectives: To describe a new porcine disc degeneration model, and to analyze disc remodeling and degeneration after nucleotomy with special view to the different...