Helene Justiniano
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Explore the profile of Helene Justiniano including associated specialties, affiliations and a list of published articles.
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12
Citations
100
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Recent Articles
1.
Legrand M, Mousson A, Carl P, Rosse L, Justiniano H, Gies J, et al.
Cell Death Dis
. 2023 Mar;
14(3):190.
PMID: 36899008
Cell invasion is a highly complex process that requires the coordination of cell migration and degradation of the extracellular matrix. In melanoma cells, as in many highly invasive cancer cell...
2.
Cruz Da Silva E, Foppolo S, Lhermitte B, Ingremeau M, Justiniano H, Klein L, et al.
Pharmaceutics
. 2022 Oct;
14(10).
PMID: 36297416
Nucleic-acid aptamers are of strong interest for diagnosis and therapy. Compared with antibodies, they are smaller, stable upon variations in temperature, easy to modify, and have higher tissue-penetration abilities. However,...
3.
Legeay S, Tran K, Abatuci Y, Justiniano H, Lugnier C, Duval O, et al.
Curr Pharm Des
. 2019 Feb;
24(46):5580-5589.
PMID: 30727871
Background: Among polyphenolic compounds suggested to prevent cardiovascular diseases (CVDs) and to explain the "French paradox", the anthocyanidin delphinidin (Dp) has been reported to support at least partly the vascular...
4.
Abou-Jaoude A, Badique L, Mlih M, Awan S, Guo S, Lemle A, et al.
Sci Rep
. 2018 Jun;
8(1):9577.
PMID: 29921842
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
5.
Abou-Jaoude A, Badique L, Mlih M, Awan S, Guo S, Lemle A, et al.
Sci Rep
. 2018 Mar;
8(1):4501.
PMID: 29540796
ShcA is an adaptor protein that binds to the cytoplasmic tail of receptor tyrosine kinases and of the Low Density Lipoprotein-related receptor 1 (LRP1), a trans-membrane receptor that protects against...
6.
El Asmar Z, Terrand J, Jenty M, Host L, Mlih M, Zerr A, et al.
J Biol Chem
. 2016 Jan;
291(10):5116-27.
PMID: 26792864
The low density lipoprotein receptor-related protein 1 (LRP1) is a ubiquitously expressed cell surface receptor that protects from intracellular cholesterol accumulation. However, the underlying mechanisms are unknown. Here we show...
7.
Keravis T, Favot L, Abusnina A, Anton A, Justiniano H, Soleti R, et al.
PLoS One
. 2015 Dec;
10(12):e0145291.
PMID: 26694325
The vasculoprotective properties of delphinidin are driven mainly by its action on endothelial cells. Moreover, delphinidin displays anti-angiogenic properties in both in vitro and in vivo angiogenesis models and thereby...
8.
Abusnina A, Keravis T, Zhou Q, Justiniano H, Lobstein A, Lugnier C
Thromb Haemost
. 2014 Sep;
113(2):319-28.
PMID: 25230992
Vascular endothelial growth factor (VEGF) plays a major role in angiogenesis by stimulating endothelial cells. Increase in cyclic AMP (cAMP) level inhibits VEGF-induced endothelial cell proliferation and migration. Cyclic nucleotide...
9.
Kummerle A, Schmitt M, Cardozo S, Lugnier C, Villa P, Lopes A, et al.
J Med Chem
. 2012 Aug;
55(17):7525-45.
PMID: 22891752
Among a small series of tested N-acylhydrazones (NAHs), the compound 8a was selected as a selective submicromolar phosphodiesterase-4 (PDE4) inhibitor associated with anti-TNF-α properties measured both in vitro and in...
10.
Bihel F, Justiniano H, Schmitt M, Hellal M, Ibrahim M, Lugnier C, et al.
Bioorg Med Chem Lett
. 2011 Sep;
21(21):6567-72.
PMID: 21920746
Pharmacophoric comparison between papaverine and tofisopam led to identify three new series of micro- to sub-micromolar inhibitors of phosphodiesterase-4, including 7,8-dialkoxy-2,3-benzodiazepin-4-one derivatives, 7,8-dialkoxy-1,4-benzodiazepin-2-one derivatives, and dialkoxybenzophenone derivatives.