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Daniel A Heller

Explore the profile of Daniel A Heller including associated specialties, affiliations and a list of published articles. Areas
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Articles 93
Citations 3138
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Recent Articles
1.
Piletsky S, Keblish E, Heller D
Nano Lett . 2025 Feb; 25(6):2480-2485. PMID: 39898587
Quantum well defect-modified single-walled carbon nanotubes are nanomaterials with wide-ranging applications in biosensing, imaging, quantum computing, and catalysis. The most common method for covalent functionalization of nanotubes for biosensing applications...
2.
Vogt K, Silberman P, Lin Q, Han J, Laflin A, Gellineau H, et al.
Sci Adv . 2025 Jan; 11(4):eads3403. PMID: 39841845
A major limiting factor in the success of chimeric antigen receptor (CAR) T cell therapy for the treatment of solid tumors is targeting tumor antigens also found on normal tissues....
3.
Larney B, Sonay A, Apfelbaum E, Mostafa N, Monette S, Goerzen D, et al.
Nat Biomed Eng . 2024 Sep; 8(9):1092-1108. PMID: 39251765
The efficacy of fluorescence-guided surgery in facilitating the real-time delineation of tumours depends on the optical contrast of tumour tissue over healthy tissue. Here we show that CJ215-a commercially available,...
4.
Yamaguchi S, Sedaka R, Kapadia C, Huang J, Hsu J, Berryhill T, et al.
Sci Rep . 2024 Jul; 14(1):15140. PMID: 38956234
Rapamycin slows cystogenesis in murine models of polycystic kidney disease (PKD) but failed in clinical trials, potentially due to insufficient drug dosing. To improve drug efficiency without increasing dose, kidney-specific...
5.
Keshari K, Heller D, Boltyanskiy R, Hricak H, Magaldi T, Overholtzer M
Cancer Cell . 2024 Jun; 42(7):1138-1141. PMID: 38848719
While cancer research and care have benefited from revolutionary advances in the ability to manipulate and study living systems, the field is limited by a lack of synergy to leverage...
6.
Kim M, McCann J, Fortner J, Randall E, Chen C, Chen Y, et al.
J Am Chem Soc . 2024 Apr; 146(18):12454-12462. PMID: 38687180
Quantum defects in single-walled carbon nanotubes promote exciton localization, which enables potential applications in biodevices and quantum light sources. However, the effects of local electric fields on the emissive energy...
7.
Sia T, Yaari Z, Feiner R, Smith E, Da Cruz Paula A, Selenica P, et al.
Gynecol Oncol Rep . 2024 Feb; 51:101330. PMID: 38356691
Given the tubal origin of high-grade serous ovarian cancer (HGSC), we sought to investigate intrauterine lavage (IUL) as a novel method of biomarker detection. IUL and serum samples were collected...
8.
Chen C, Wu Y, Wang S, Berisha N, Manzari M, Vogt K, et al.
Nat Commun . 2023 Dec; 14(1):8340. PMID: 38097573
Drug nanoaggregates are particles that can deleteriously cause false positive results during drug screening efforts, but alternatively, they may be used to improve pharmacokinetics when developed for drug delivery purposes....
9.
Antman-Passig M, Yaari Z, Goerzen D, Parikh R, Chatman S, Komer L, et al.
Nano Lett . 2023 Oct; 23(23):10687-10695. PMID: 37889874
Dysregulated lipid metabolism contributes to neurodegenerative pathologies and neurological decline in lysosomal storage disorders as well as more common neurodegenerative diseases. Niemann-Pick type A (NPA) is a fatal neurodegenerative lysosomal...
10.
Larney B, Kim M, Roberts S, Skubal M, Hsu H, Ogirala A, et al.
J Nucl Med . 2023 Aug; 64(10):1647-1653. PMID: 37620049
Shortwave infrared (900-1,700 nm) fluorescence imaging (SWIRFI) has shown significant advantages over visible (400-650 nm) and near-infrared (700-900 nm) fluorescence imaging (reduced autofluorescence, improved contrast, tissue resolution, and depth sensitivity)....