Helen E Parkinson
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Explore the profile of Helen E Parkinson including associated specialties, affiliations and a list of published articles.
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12
Citations
1559
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Recent Articles
1.
Rehm H, Page A, Smith L, Adams J, Alterovitz G, Babb L, et al.
Cell Genom
. 2022 Jan;
1(2).
PMID: 35072136
The Global Alliance for Genomics and Health (GA4GH) aims to accelerate biomedical advances by enabling the responsible sharing of clinical and genomic data through both harmonized data aggregation and federated...
2.
Zhang T, Xie P, Dong Y, Liu Z, Zhou F, Pan D, et al.
PLoS Genet
. 2020 Jan;
16(1):e1008577.
PMID: 31929527
Circadian systems provide a fitness advantage to organisms by allowing them to adapt to daily changes of environmental cues, such as light/dark cycles. The molecular mechanism underlying the circadian clock...
3.
Munoz-Fuentes V, Cacheiro P, Meehan T, Aguilar-Pimentel J, Brown S, Flenniken A, et al.
Conserv Genet
. 2018 Aug;
19(4):995-1005.
PMID: 30100824
The International Mouse Phenotyping Consortium (IMPC) is building a catalogue of mammalian gene function by producing and phenotyping a knockout mouse line for every protein-coding gene. To date, the IMPC...
4.
Rozman J, Rathkolb B, Oestereicher M, Schutt C, Ravindranath A, Leuchtenberger S, et al.
Nat Commun
. 2018 Jan;
9(1):288.
PMID: 29348434
Metabolic diseases are a worldwide problem but the underlying genetic factors and their relevance to metabolic disease remain incompletely understood. Genome-wide research is needed to characterize so-far unannotated mammalian metabolic...
5.
Dickinson M, Flenniken A, Ji X, Teboul L, Wong M, White J, et al.
Nature
. 2017 Nov;
551(7680):398.
PMID: 29144450
This corrects the article DOI: 10.1038/nature19356.
6.
Bowl M, Simon M, Ingham N, Greenaway S, Santos L, Cater H, et al.
Nat Commun
. 2017 Oct;
8(1):886.
PMID: 29026089
The developmental and physiological complexity of the auditory system is likely reflected in the underlying set of genes involved in auditory function. In humans, over 150 non-syndromic loci have been...
7.
Dickinson M, Flenniken A, Ji X, Teboul L, Wong M, White J, et al.
Nature
. 2016 Sep;
537(7621):508-514.
PMID: 27626380
Approximately one-third of all mammalian genes are essential for life. Phenotypes resulting from knockouts of these genes in mice have provided tremendous insight into gene function and congenital disorders. As...
8.
Petryszak R, Keays M, Tang Y, Fonseca N, Barrera E, Burdett T, et al.
Nucleic Acids Res
. 2015 Oct;
44(D1):D746-52.
PMID: 26481351
Expression Atlas (http://www.ebi.ac.uk/gxa) provides information about gene and protein expression in animal and plant samples of different cell types, organism parts, developmental stages, diseases and other conditions. It consists of...
9.
Petryszak R, Burdett T, Fiorelli B, Fonseca N, Gonzalez-Porta M, Hastings E, et al.
Nucleic Acids Res
. 2013 Dec;
42(Database issue):D926-32.
PMID: 24304889
Expression Atlas (http://www.ebi.ac.uk/gxa) is a value-added database providing information about gene, protein and splice variant expression in different cell types, organism parts, developmental stages, diseases and other biological and experimental...
10.
Swertz M, van der Velde K, Tesson B, Scheltema R, Arends D, Vera G, et al.
Genome Biol
. 2010 Mar;
11(3):R27.
PMID: 20214801
We present an extensible software model for the genotype and phenotype community, XGAP. Readers can download a standard XGAP (http://www.xgap.org) or auto-generate a custom version using MOLGENIS with programming interfaces...