Hejer Dhahri
Overview
Explore the profile of Hejer Dhahri including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
3
Followers
0
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Recent Articles
1.
Hegazy Y, Dhahri H, El Osmani N, George S, Chandler D, Fondufe-Mittendorf Y
J Biol Chem
. 2024 Dec;
301(1):108048.
PMID: 39638247
Histone proteins organize nuclear DNA in eukaryotic cells and play crucial roles in regulating chromatin structure and function. Histone variants are produced by distinct histone genes and are produced independently...
2.
Saintilnord W, Hegazy Y, Chesnutt K, Eckstein M, Cassidy R, Dhahri H, et al.
bioRxiv
. 2024 Nov;
PMID: 39605447
Chromatin architecture governs DNA accessibility and gene expression. Thus, any perturbations to chromatin can significantly alter gene expression programs and promote disease. Prior studies demonstrate that every amino acid in...
3.
Dhahri H, Saintilnord W, Chandler D, Fondufe-Mittendorf Y
Int J Mol Sci
. 2024 Jun;
25(12).
PMID: 38928493
The incorporation of histone variants has structural ramifications on nucleosome dynamics and stability. Due to their unique sequences, histone variants can alter histone-histone or histone-DNA interactions, impacting the folding of...
4.
Dhahri H, Fondufe-Mittendorf Y
Wiley Interdiscip Rev RNA
. 2023 Nov;
:e1823.
PMID: 37957925
PARP1 (poly-ADP-ribose polymerase 1) is a multidomain protein with a flexible and self-folding structure that allows it to interact with a wide range of biomolecules, including nucleic acids and target...
5.
Dhahri H, Matveeva E, Fondufe-Mittendorf Y
Methods Mol Biol
. 2022 Dec;
2609:315-328.
PMID: 36515843
The rate of RNA polymerase II (RNAPII) transcriptional elongation plays a critical role in mRNA biogenesis, from transcription initiation to alternative splicing. As RNAPII moves along the DNA, it must...
6.
Matveeva E, Dhahri H, Fondufe-Mittendorf Y
Cells
. 2022 Oct;
11(20).
PMID: 36291070
RNA polymerase elongation along the gene body is tightly regulated to ensure proper transcription and alternative splicing events. Understanding the mechanism and factors critical in regulating the rate of RNA...