Heike Vogel
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Explore the profile of Heike Vogel including associated specialties, affiliations and a list of published articles.
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63
Citations
1239
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Recent Articles
1.
Gaugel J, Jahnert M, Neumann A, Heyd F, Schurmann A, Vogel H
J Nutr Biochem
. 2024 Dec;
137:109837.
PMID: 39725041
Alternative splicing contributes to diversify the cellular protein landscape, but aberrant splicing is implicated in many diseases. To which extent mis-splicing contributes to insulin resistance as the causal defect of...
2.
Gaugel J, Haacke N, Sehgal R, Jahnert M, Jonas W, Hoffmann A, et al.
Mol Metab
. 2024 Aug;
88:102014.
PMID: 39182843
Objective: Picalm (phosphatidylinositol-binding clathrin assembly protein), a ubiquitously expressed clathrin-adapter protein, is a well-known susceptibility gene for Alzheimer's disease, but its role in white adipose tissue (WAT) function has not...
3.
Heinen D, Heissel A, Heinzel S, Fydrich T, Strohle A, Rapp M, et al.
BMC Public Health
. 2023 Dec;
23(1):2509.
PMID: 38098007
Background: Depression is a leading cause of disability worldwide and a significant contributor to the global burden of disease. Altered leptin levels are known to be associated with depressive symptoms,...
4.
Altenhofen D, Khuong J, Kuhn T, Lebek S, Gorigk S, Kaiser K, et al.
Int J Mol Sci
. 2023 Jan;
24(1).
PMID: 36614300
Type 2 diabetes (T2D) represents a multifactorial metabolic disease with a strong genetic predisposition. Despite elaborate efforts in identifying the genetic variants determining individual susceptibility towards T2D, the majority of...
5.
van Egmond L, Meth E, Engstrom J, Ilemosoglou M, Keller J, Vogel H, et al.
Obesity (Silver Spring)
. 2022 Nov;
31(3):635-641.
PMID: 36404495
Objective: This study investigated whether blood concentrations of leptin, ghrelin, and adiponectin are affected by acute total sleep deprivation in a sex- and weight-specific manner. Methods: A total of 44...
6.
Kuhn T, Kaiser K, Lebek S, Altenhofen D, Knebel B, Herwig R, et al.
Hum Mol Genet
. 2022 Jul;
31(23):4019-4033.
PMID: 35796564
To nominate novel disease genes for obesity and type 2 diabetes (T2D), we recently generated two mouse backcross populations of the T2D-susceptible New Zealand Obese (NZO/HI) mouse strain and two...
7.
Hauffe R, Rath M, Agyapong W, Jonas W, Vogel H, Schulz T, et al.
Antioxidants (Basel)
. 2022 May;
11(5).
PMID: 35624726
The intake of high-fat diets (HFDs) containing large amounts of saturated long-chain fatty acids leads to obesity, oxidative stress, inflammation, and insulin resistance. The trace element selenium, as a crucial...
8.
Gorigk S, Ouwens D, Kuhn T, Altenhofen D, Binsch C, Damen M, et al.
Biochim Biophys Acta Mol Cell Biol Lipids
. 2022 Apr;
1867(6):159153.
PMID: 35367353
Changes in intracellular CoA levels are known to contribute to the development of non-alcoholic fatty liver disease (NAFLD) in type 2 diabetes (T2D) in human and rodents. However, the underlying...
9.
Jonas W, Kluth O, Helms A, Voss S, Jahnert M, Gottmann P, et al.
Int J Mol Sci
. 2022 Mar;
23(6).
PMID: 35328627
Current attempts to prevent and manage type 2 diabetes have been moderately effective, and a better understanding of the molecular roots of this complex disease is important to develop more...
10.
Aga H, Soultoukis G, Stadion M, Garcia-Carrizo F, Jahnert M, Gottmann P, et al.
Int J Mol Sci
. 2022 Feb;
23(4).
PMID: 35216219
Pancreatic steatosis associates with β-cell failure and may participate in the development of type-2-diabetes. Our previous studies have shown that diabetes-susceptible mice accumulate more adipocytes in the pancreas than diabetes-resistant...