Heike Goebel
Overview
Explore the profile of Heike Goebel including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
484
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Recent Articles
11.
de Boer O, Li X, Goebel H, van der Wal A
J Clin Pathol
. 2015 Jul;
69(2):181-2.
PMID: 26205971
No abstract available.
12.
Ebner K, Feldkoetter M, Ariceta G, Bergmann C, Buettner R, Doyon A, et al.
BMC Nephrol
. 2015 Apr;
16:22.
PMID: 25886171
Background: Autosomal recessive polycystic kidney disease (ARPKD) is a rare but frequently severe disorder that is typically characterized by cystic kidneys and congenital hepatic fibrosis but displays pronounced phenotypic heterogeneity....
13.
Tittelbach-Helmrich D, Bausch D, Drognitz O, Goebel H, Schulz-Huotari C, Kramer-Zucker A, et al.
Case Rep Med
. 2014 Oct;
2014:613641.
PMID: 25317177
We present a case report of a 59-year-old man, who received a blood group identical living unrelated kidney graft. This was his second kidney transplantation. Pretransplant T-cell crossmatch resulted negative....
14.
Gee H, Saisawat P, Ashraf S, Hurd T, Vega-Warner V, Fang H, et al.
J Clin Invest
. 2013 Jul;
123(8):3243-53.
PMID: 23867502
Nephrotic syndrome (NS) is divided into steroid-sensitive (SSNS) and -resistant (SRNS) variants. SRNS causes end-stage kidney disease, which cannot be cured. While the disease mechanisms of NS are not well...
15.
Dunkern T, Chavan S, Bankar D, Patil A, Kulkarni P, Kharkar P, et al.
J Enzyme Inhib Med Chem
. 2013 May;
29(3):408-19.
PMID: 23663081
This study is based on our attempts to further explore the structure-activity relationship (SAR) of VX-148 (3) in an attempt to identify inosine 5'-mono-phosphate dehydrogenase (IMPDH) inhibitors superior to mycophenolic...
16.
Dunkern T, Prabhu A, Kharkar P, Goebel H, Rolser E, Burckhard-Boer W, et al.
J Comput Aided Mol Des
. 2012 Nov;
26(11):1277-92.
PMID: 23117549
IMPDH (Inosine 5'-monophosphate dehydrogenase) catalyzes a rate-limiting step in the de novo biosynthesis of guanine nucleotides. IMPDH inhibition in sensitive cell types (e.g., lymphocytes) blocks proliferation (by blocking RNA and...
17.
Brahler S, Ising C, Hagmann H, Rasmus M, Hoehne M, Kurschat C, et al.
Am J Physiol Renal Physiol
. 2012 Sep;
303(10):F1473-85.
PMID: 22975019
Inflammation conveys the development of glomerular injury and is a major cause of progressive kidney disease. NF-κB signaling is among the most important regulators of proinflammatory signaling. Its role in...
18.
Beck B, Habbig S, Dittrich K, Stippel D, Kaul I, Koerber F, et al.
Nephrol Dial Transplant
. 2012 Jan;
27(7):2984-9.
PMID: 22287658
Background: The infantile form of primary hyperoxaluria type I (PHI) is the most devastating PH subtype leading to early end-stage renal failure and severe systemic oxalosis. Combined or sequential liver-kidney...
19.
Angelini A, Andersen C, Bartoloni G, Black F, Bishop P, Doran H, et al.
J Heart Lung Transplant
. 2011 Aug;
30(11):1214-20.
PMID: 21816625
Background: The aim of this study was to assess, at the European level and using digital technology, the inter-pathologist reproducibility of the ISHLT 2004 system and to compare it with...
20.
Ochtrop M, Goldacker S, May A, Rizzi M, Draeger R, Hauschke D, et al.
Blood
. 2011 May;
118(2):309-18.
PMID: 21576700
In common variable immunodeficiency (CVID) defects in early stages of B-cell development, bone marrow (BM) plasma cells and T lymphocytes have not been studied systematically. Here we report the first...