Heike Goebel
Overview
Explore the profile of Heike Goebel including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
484
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0
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Recent Articles
1.
Inholz K, Anderl J, Klawitter M, Goebel H, Maurits E, Kirk C, et al.
Eur J Immunol
. 2024 Mar;
54(4):e2350613.
PMID: 38458995
Immunoproteasomes are a special class of proteasomes, which can be induced with IFN-γ in an inflammatory environment. In recent years, it became evident that certain immune cell types constitutively express...
2.
Hamdorf M, Imhof T, Bailey-Elkin B, Betz J, Theobald S, Simonis A, et al.
J Mol Cell Biol
. 2023 Oct;
15(10).
PMID: 37891014
The novel coronavirus pandemic, first reported in December 2019, was caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 infection leads to a strong immune response and activation...
3.
Oliveri F, Keller S, Goebel H, Alvarez Salinas G, Basler M
Life Sci Alliance
. 2023 Apr;
6(6).
PMID: 37012049
Ubiquitin-independent protein degradation via the 20S proteasome without the 19S regulatory particle has gained increasing attention over the last years. The degradation of the ubiquitin-like modifier FAT10 by the 20S...
4.
Knipper K, Lyu S, Goebel H, Damanakis A, Zhao Y, Bruns C, et al.
J Cancer Res Clin Oncol
. 2022 Dec;
149(9):5531-5538.
PMID: 36472768
Purpose: Pancreatic ductal adenocarcinoma (PDAC) is currently one of the leading causes of cancer death worldwide. Therefore, building further subgroups as well as enabling individual patient therapy and diagnostics are...
5.
Goebel H, Koeditz B, Huerta M, Kameri E, Nestler T, Kamphausen T, et al.
Biomedicines
. 2022 Apr;
10(4).
PMID: 35453608
In December 2019, the first case of COVID-19 was reported and since then several groups have already published that the virus can be present in the testis. To study the...
6.
Basler M, Christ M, Goebel H, Groettrup M
J Immunol
. 2021 Mar;
206(8):1697-1708.
PMID: 33731337
The prime function of proteasomes is the control of protein homeostasis in cells (i.e., the removal of proteins that are not properly folded, damaged by stress conditions like reactive oxygen...
7.
Pawar A, Basler M, Goebel H, Alvarez Salinas G, Groettrup M, Bottcher T
ACS Cent Sci
. 2020 Mar;
6(2):241-246.
PMID: 32123742
We have developed a syringolin-based chemical probe and explored its utility for the profiling of metabolite extracts as potent inhibitors of the 20S proteasome. Activity-guided fractionation by competitive labeling allowed...
8.
Basler M, Claus M, Klawitter M, Goebel H, Groettrup M
J Immunol
. 2019 Sep;
203(7):1776-1785.
PMID: 31484727
MECL-1 (β2i), LMP2 (β1i), and LMP7 (β5i) are the proteolytically active subunits of the immunoproteasome (IP), a special type of proteasome mainly expressed in hematopoietic cells. Targeting the IP in...
9.
Burgmaier K, Kunzmann K, Ariceta G, Bergmann C, Buescher A, Burgmaier M, et al.
J Pediatr
. 2018 May;
199:22-28.e6.
PMID: 29753540
Objective: To identify prenatal, perinatal, and postnatal risk factors for dialysis within the first year of life in children with autosomal recessive polycystic kidney disease (ARPKD) as a basis for...
10.
Taylan C, Goebel H, Beck B, Dotsch J, Nuesken K, Hoppe B, et al.
Am J Kidney Dis
. 2016 Nov;
68(6):A18-A21.
PMID: 27884282
No abstract available.