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Hee Kim

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Articles 48
Citations 594
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Recent Articles
1.
Zhen G, Do N, Manh N, Ha H, Kim H, Kim H, et al.
Pharmaceuticals (Basel) . 2025 Feb; 18(2). PMID: 40006019
Pain is a complex condition influenced by peripheral, central, immune, and psychological factors. Multitarget approaches offer a more effective and safer alternative to single-target analgesics by enhancing efficacy, reducing side...
2.
Hwang H, Kim H
Brain Sci . 2023 Jul; 13(7). PMID: 37509000
(1) Background: Stroke patients are exposed to various psychosocial factors, such as depression, anxiety, and stress, which can cause problems with respect to their quality of sleep and social participation....
3.
Merjaneh N, Kim H, Escoto H, Metts J, Ray A, Bukowinski A, et al.
J Pediatr Hematol Oncol . 2023 Jan; 45(6):315-321. PMID: 36706311
BCOR alterations are described in ultra-rare infantile soft tissue sarcomas including primitive myxoid mesenchymal tumor of infancy and undifferentiated round cell sarcoma (URCS). Previous reports often describe dismal outcomes. Thus,...
4.
Lim Y, Lee J, Kim S, Cha T, Yoo D, Kim H
Hong Kong J Occup Ther . 2022 Dec; 35(2):180-189. PMID: 36467523
Cooperation among rehabilitation team members is essential in the home-based rehabilitation setting. Q-methodology that can quantitatively analyze the subjectivity of members of the rehabilitation team was used to explore the...
5.
Manh N, Hoang V, Ngo V, Kang S, Jeong J, Ha H, et al.
Eur J Med Chem . 2022 Oct; 244:114837. PMID: 36265279
The toxic pyroglutamate form of amyloid-β (pE-Aβ) is important for the pathogenesis of early Alzheimer's disease (AD); therefore, reducing pE-Aβ by inhibiting glutaminyl cyclase (QC) provides a promising strategy for...
6.
Park E, Song K, Kim D, Lee M, Manh N, Kim H, et al.
ACS Med Chem Lett . 2022 Sep; 13(9):1459-1467. PMID: 36105338
Glutaminyl cyclases (QC, isoQC) convert N-terminal glutamine or glutamate into pyroglutamate (pGlu) on substrates. IsoQC has recently been demonstrated to promote pGlu formation on the N-terminus of CD47, the SIRPα...
7.
Li X, Han J, Bujaranipalli S, He J, Kim E, Kim H, et al.
Eur J Med Chem . 2022 May; 238:114444. PMID: 35588599
The neurofibrillary tangles (NFTs) formed from hyperphosphorylation of tau protein are closely associated with Alzheimer's disease (AD). O-GlcNAcylation of tau can negatively regulate hyperphosphorylation and the O-GlcNAcase (OGA) catalyzes the...
8.
Alexandrou E, Dauber A, Tyzinski L, Hwa V, Andrew M, Kim H, et al.
Am J Med Genet A . 2022 Jan; 188(4):1193-1203. PMID: 35001504
Aggrecan is a proteoglycan within the physeal and articular cartilage. Aggrecan deficiency, due to heterozygous mutations in the ACAN gene, causes dominantly inherited short stature and, in many patients, early-onset...
9.
Manh N, Hoang V, Ngo V, Ann J, Jang T, Ha J, et al.
Eur J Med Chem . 2021 Sep; 226:113819. PMID: 34536669
The inhibition of glutaminyl cyclase (QC) may provide a promising strategy for the treatment of early Alzheimer's disease (AD) by reducing the amount of the toxic pyroform of β-amyloid (Aβ)...
10.
Kim H, Ganslandt T, Miethke T, Neumaier M, Kittel M
JMIR Res Protoc . 2020 Jul; 9(7):e16843. PMID: 32673276
Background: In recent years, remarkable progress has been made in deep learning technology and successful use cases have been introduced in the medical domain. However, not many studies have considered...