Hazel Cheng
Overview
Explore the profile of Hazel Cheng including associated specialties, affiliations and a list of published articles.
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11
Citations
369
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Recent Articles
1.
Solorzano-Vargas R, Bjerknes M, Wang J, Wu S, Garcia-Careaga M, Pitukcheewanont P, et al.
JCI Insight
. 2019 Dec;
5(1).
PMID: 31805014
Biallelic mutations of the gene encoding the transcription factor NEUROG3 are associated with a rare disorder that presents in neonates as generalized malabsorption - due to a complete absence of...
2.
Solorzano-Vargas R, Bjerknes M, Wu S, Wang J, Stelzner M, Dunn J, et al.
J Biol Chem
. 2019 Jul;
294(41):15182-15192.
PMID: 31341016
Neurogenin-3 (NEUROG3) is a helix-loop-helix (HLH) transcription factor involved in the production of endocrine cells in the intestine and pancreas of humans and mice. However, the human NEUROG3 loss-of-function phenotype...
3.
McNitt C, Cheng H, Ullrich S, Popik V, Bjerknes M
J Am Chem Soc
. 2017 Sep;
139(40):14029-14032.
PMID: 28925255
Irradiation of cyclopropenone-masked dibenzocyclooctynes with near-infrared pulses from a femtosecond laser triggers photodecarbonylation via nonresonant two- or three-photon excitation. Multiphoton-generated cyclooctynes undergo a SPAAC reaction with organic azides, yielding the...
4.
Bjerknes M, Cheng H, McNitt C, Popik V
Bioconjug Chem
. 2017 Apr;
28(5):1560-1565.
PMID: 28437092
Little is known about the reactivity of strain-promoted alkyne-azide cycloaddition (SPAAC) reagents with inorganic azides. We explore the reactions of a variety of popular SPAAC reagents with sodium azide and...
5.
Bjerknes M, Khandanpour C, Moroy T, Fujiyama T, Hoshino M, Klisch T, et al.
Dev Biol
. 2011 Dec;
362(2):194-218.
PMID: 22185794
Mix progenitors are short-lived multipotential cells formed as intestinal epithelial stem cells initiate a differentiation program. Clone dynamics indicates that various epithelial cell lineages arise from Mix via a sequence...
6.
Bjerknes M, Cheng H
Dev Biol
. 2010 Jul;
345(1):49-63.
PMID: 20599897
Elucidating the mechanisms determining multipotent progenitor cell fate remains a fundamental project of contemporary biology. Various tissues of mice and men with defects in the zinc-finger transcriptional repressor Gfi1 have...
7.
Bjerknes M, Cheng H
Methods Enzymol
. 2006 Dec;
419:337-83.
PMID: 17141062
The adult intestinal epithelium contains a relatively simple, highly organized, and readily accessible stem cell system. Excellent methods exist for the isolation of intestinal epithelium from adults, and as a...
8.
Bjerknes M, Cheng H
Dev Biol
. 2006 Sep;
300(2):722-35.
PMID: 17007831
It is thought that small intestinal epithelial stem cell progeny, via Notch signaling, yield a Hes1-expressing columnar lineage progenitor and an Atoh1 (also known as Math1)-expressing common progenitor for all...
9.
10.
Bjerknes M, Cheng H
Am J Physiol Gastrointest Liver Physiol
. 2005 Aug;
289(3):G381-7.
PMID: 16093419
Current views of the identity, distribution, and regulation of small intestinal epithelial stem cells and their immediate progeny are discussed. Recent works implicating Wnt signaling in stem and progenitor proliferation,...