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Hatice Karauzum

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Articles 22
Citations 537
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Recent Articles
1.
Wang Y, Mukherjee I, Venkatasubramaniam A, Dikeman D, Orlando N, Zhang J, et al.
Front Immunol . 2024 Apr; 15:1373367. PMID: 38633244
is the leading cause of skin and soft tissue infections (SSTIs) in the U.S. as well as more serious invasive diseases, including bacteremia, sepsis, endocarditis, surgical site infections, osteomyelitis, and...
2.
Kanevsky I, Surendran N, McElwee K, Lei L, Watson W, Pride M, et al.
Vaccine . 2023 Oct; 41(45):6625-6629. PMID: 37793976
Aim: Pneumococcal conjugate vaccines (PCV13, PCV15, PCV20) effectively target the capsular polysaccharides of the most common disease-causing Streptococcus pneumoniae serotypes. In this short communication, we analyzed healthy participants who received...
3.
Andrianov A, Marin A, Wang R, Karauzum H, Chowdhury A, Agnihotri P, et al.
ACS Appl Bio Mater . 2021 Apr; 3(5):3187-3195. PMID: 33880435
Resiquimod or R848 (RSQD) is a Toll-like receptor (TLR) 7/8 agonist which shows promise as vaccine adjuvant due to its potential to promote highly desirable cellular immunity. The development of...
4.
Karauzum H, Venkatasubramaniam A, Adhikari R, Kort T, Holtsberg F, Mukherjee I, et al.
Front Immunol . 2021 Mar; 12:624310. PMID: 33777005
causes a wide range of diseases from skin infections to life threatening invasive diseases such as bacteremia, endocarditis, pneumonia, surgical site infections, and osteomyelitis. Skin infections such as furuncles, carbuncles,...
5.
Venkatasubramaniam A, Liao G, Cho E, Adhikari R, Kort T, Holtsberg F, et al.
Front Immunol . 2021 Mar; 12:621754. PMID: 33717122
is a leading cause of significant morbidity and mortality and an enormous economic burden to public health worldwide. Infections caused by methicillin-resistant (MRSA) pose a major threat as MRSA strains...
6.
Castro C, Rosenzwajg M, Carapito R, Shahrooei M, Konantz M, Khan A, et al.
J Exp Med . 2020 Aug; 217(12). PMID: 32766723
The Nck-associated protein 1-like (NCKAP1L) gene, alternatively called hematopoietic protein 1 (HEM-1), encodes a hematopoietic lineage-specific regulator of the actin cytoskeleton. Nckap1l-deficient mice have anomalies in lymphocyte development, phagocytosis, and...
7.
Kailasan S, Kort T, Mukherjee I, Liao G, Kanipakala T, Williston N, et al.
Toxins (Basel) . 2019 Jun; 11(6). PMID: 31207937
(SA) infections cause high mortality and morbidity in humans. Being central to its pathogenesis, thwarts the host defense by secreting a myriad of virulence factors, including bicomponent, pore-forming leukotoxins. While...
8.
Chen G, Karauzum H, Long H, Carranza D, Holtsberg F, Howell K, et al.
J Mol Biol . 2019 Apr; 431(21):4354-4367. PMID: 30928493
To develop an antibody (Ab) therapeutic against staphylococcal enterotoxin B (SEB), a potential incapacitating bioterrorism agent and a major cause of food poisoning, we developed a "class T" anti-SEB neutralizing...
9.
Venkatasubramaniam A, Adhikari R, Kort T, Liao G, Conley S, Abaandou L, et al.
Sci Rep . 2019 Mar; 9(1):3279. PMID: 30824769
Superantigens (SAgs) play a major role in the pathogenesis of Staphylococcus aureus and are associated with several diseases, including food poisoning, bacterial arthritis, and toxic shock syndrome. Monoclonal antibodies to...
10.
Verreault D, Ennis J, Whaley K, Killeen S, Karauzum H, Aman M, et al.
Antimicrob Agents Chemother . 2019 Feb; 63(5). PMID: 30782986
Staphylococcal enterotoxin B (SEB) is a protein exotoxin found on the cell surface of that is the source for multiple pathologies in humans. When purified and concentrated in aerosol form,...