Harun Patel
Overview
Explore the profile of Harun Patel including associated specialties, affiliations and a list of published articles.
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Articles
96
Citations
497
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Recent Articles
1.
Patil S, Patil S, Asgaonkar K, Bhandari S, Edake A, Patel H, et al.
Chem Biodivers
. 2025 Feb;
:e202403150.
PMID: 39936224
The epidermal growth factor receptor (EGFR) regulates cell survival and proliferation, making it a key therapeutic target in cancer. EGFR tyrosine kinase inhibitors (TKIs) block EGFR signaling, preventing uncontrolled cell...
2.
Ahmad I, Patel H
J Biochem Mol Toxicol
. 2024 Dec;
39(1):e70077.
PMID: 39717895
A series of 2,4-disubstituted pyrimidine derivatives bearing 5-substituted-1,3,4 thidiazole were devised and synthesized based on the binding mode of the approved drug Osimertinib with the ATP competitive site of EGFR-L858R/T790M...
3.
Shaikh M, Patel H
Bioorg Med Chem
. 2024 Dec;
118():118025.
PMID: 39631241
Tuberculosis (TB) remains a significant global health challenge, with multidrug-resistant (MDR-TB) and extensively drug-resistant (XDR-TB) strains posing severe threats to treatment efficacy. Linezolid, a key component of the BPaL (Bedaquiline,...
4.
Ipe R, Oh J, Kumar S, Ahmad I, Nath L, Bindra S, et al.
Mol Divers
. 2024 Aug;
PMID: 39145880
Eighteen compounds derived from two sub-series, (HC1-HC9) and (HF1-HF9), were synthesized and evaluated for their inhibitory activities against monoamine oxidase (MAO). HC (chalcone) series showed higher inhibitory activity against MAO-B...
5.
Alhagri I, Alsowayan R, Ghannay S, Al-Hazmy S, Ahmad I, Patel H, et al.
Heliyon
. 2024 Aug;
10(14):e34561.
PMID: 39113987
are well explored among versatile and outstanding class of pharmacophores for the preparation and discovery of drugs. Herein, the electronic absorption and emission spectra of were investigated in three different...
6.
Chandole P, Pawar T, Olivares-Romero J, Tivari S, Garcia Lara B, Patel H, et al.
RSC Adv
. 2024 Jun;
14(25):17710-17723.
PMID: 38832247
Antimicrobial resistance (AMR) represents a critical challenge worldwide, necessitating the pursuit of novel approaches to counteract bacterial and fungal pathogens. In this context, we explored the potential of cationic amino...
7.
Isik A, Acar Cevik U, Karayel A, Ahmad I, Patel H, Celik I, et al.
ACS Omega
. 2024 Apr;
9(16):18469-18479.
PMID: 38680334
In this study, a series of new benzimidazole-thiadiazole hybrids were synthesized, and the synthesized compounds were screened for their antimicrobial activities against eight species of pathogenic bacteria and three fungal...
8.
Thapa S, Biradar M, Nargund S, Ahmad I, Agrawal M, Patel H, et al.
Adv Pharmacol Pharm Sci
. 2024 Apr;
2024:9986613.
PMID: 38577412
Tuberculosis, also known as TB, is a widespread bacterial infection that remains a significant global health issue. This study focuses on conducting a thorough investigation into the synthesis, evaluation of...
9.
Karande S, Das B, Acharya S, Kumar A, Patel H, Sharma A, et al.
J Biomol Struct Dyn
. 2024 Mar;
:1-13.
PMID: 38433403
Idiopathic pulmonary fibrosis (IPF) is a life-threatening disease with a survival rate of <5 years. The TGF-β plays a significant role in the progression and severity of IPF. The TGF-β...
10.
Alotayeq A, Ghannay S, Alhagri I, Ahmed I, Hammami B, Albadri A, et al.
Heliyon
. 2024 Feb;
10(4):e26341.
PMID: 38404822
A novel isoxazolidine derivative ISoXD) dye was successfully synthesized and comprehensively characterized. In this study, we conducted a thorough examination of its various properties, including optical characteristics, interactions with DNA...