Hartmut Oschkinat
Overview
Explore the profile of Hartmut Oschkinat including associated specialties, affiliations and a list of published articles.
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Articles
165
Citations
3981
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Recent Articles
1.
Yarava J, Orwick-Rydmark M, Ryoo D, Hofstetter A, Gumbart J, Habeck M, et al.
J Am Chem Soc
. 2025 Feb;
147(10):8618-8628.
PMID: 40014811
The vast majority of cells are protected and functionalized by a dense surface layer of glycans, proteoglycans, and glycolipids. This surface represents an underexplored space in structural biology that is...
2.
Chatzimpinou A, Diehl A, Harhoff A, Driller K, Vanslembrouck B, Chen J, et al.
NPJ Biofilms Microbiomes
. 2025 Feb;
11(1):23.
PMID: 39894846
Bacterial biofilms are complex cell communities within a self-produced extracellular matrix, crucial in various fields but challenging to analyze in 3D. We developed a "biofilm-in-capillary" growth method compatible with full-rotation...
3.
Gerland L, Diehl A, Erdmann N, Hiller M, Lang C, Teutloff C, et al.
Chemistry
. 2024 Nov;
31(2):e202402454.
PMID: 39541567
Phytochromes perceive subtle changes in the light environment and convert them into biological signals by photoconversion between the red-light absorbing (Pr) and the far-red-absorbing (Pfr) states. In the primitive bacteriophytochromes...
4.
Bell D, Lindemann F, Gerland L, Aucharova H, Klein A, Friedrich D, et al.
J Biomol NMR
. 2024 Jun;
78(3):179-192.
PMID: 38904893
Solution NMR is typically applied to biological systems with molecular weights < 40 kDa whereas magic-angle-spinning (MAS) solid-state NMR traditionally targets very large, oligomeric proteins and complexes exceeding 500 kDa...
5.
Bell D, Lindemann F, Gerland L, Aucharova H, Klein A, Friedrich D, et al.
Res Sq
. 2024 Mar;
PMID: 38464080
Solution NMR is typically applied to biological systems with molecular weights < 40 kDa whereas magic-angle-spinning (MAS) solid-state NMR traditionally targets very large, oligomeric proteins and complexes exceeding 500 kDa...
6.
Kamdem N, Roske Y, Kovalskyy D, Platonov M, Balinskyi O, Kreuchwig A, et al.
Magn Reson (Gott)
. 2023 Oct;
2(1):355-374.
PMID: 37904770
Dishevelled (Dvl) proteins are important regulators of the Wnt signalling pathway, interacting through their PDZ domains with the Wnt receptor Frizzled. Blocking the Dvl PDZ-Frizzled interaction represents a potential approach...
7.
Roske Y, Lindemann F, Diehl A, Cremer N, Higman V, Schlegel B, et al.
Proc Natl Acad Sci U S A
. 2023 Apr;
120(17):e2217070120.
PMID: 37068239
Studying mechanisms of bacterial biofilm generation is of vital importance to understanding bacterial cell-cell communication, multicellular cohabitation principles, and the higher resilience of microorganisms in a biofilm against antibiotics. Biofilms...
8.
Belyy A, Lindemann F, Roderer D, Funk J, Bardiaux B, Protze J, et al.
Nat Commun
. 2022 Jul;
13(1):4202.
PMID: 35858890
Tc toxins deliver toxic enzymes into host cells by a unique injection mechanism. One of these enzymes is the actin ADP-ribosyltransferase TccC3, whose activity leads to the clustering of the...
9.
Goldberga I, Li R, Chow W, Reid D, Bashtanova U, Rajan R, et al.
RSC Adv
. 2022 May;
9(46):26686-26690.
PMID: 35528564
Sensitivity enhancement by isotope enrichment and DNP NMR enables detection of minor but biologically relevant species in native intact bone, including nucleic acids, choline from phospholipid headgroups, and histidinyl and...
10.
Ellson C, Rica I, Kim J, Huang Y, Lim D, Mitra T, et al.
J Mol Biol
. 2022 Mar;
434(9):167533.
PMID: 35314146
The neutrophil NADPH oxidase produces both intracellular and extracellular reactive oxygen species (ROS). Although oxidase activity is essential for microbial killing, and ROS can act as signaling molecules in the...