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Harshath Gupta

Explore the profile of Harshath Gupta including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Gupta H, Inoue H, Nakai Y, Nakayama M, Jones T, Hicks J, et al.
Cancer Prev Res (Phila) . 2023 Jun; 16(8):449-460. PMID: 37347938
Prevention Relevance: DNA hypermethylation at the GSTP1 promoter progressively spreads from being unmethylated in normal prostate to intermediate levels in precursor lesions to extensive methylation in cancer. This molecular progression...
2.
Pham M, Gupta A, Gupta H, Vaghasia A, Skaist A, Garrison M, et al.
Mol Cancer Res . 2022 Apr; 20(7):1013-1020. PMID: 35452513
Implications: This study therefore comprehensively characterized phased genomic alterations in the commonly used prostate cancer cell lines, providing a useful resource for future prostate cancer research.
3.
Purman C, Collins P, Porter S, Saini A, Gupta H, Sleckman B, et al.
Mol Cell Biol . 2019 Oct; 39(24). PMID: 31591143
DNA damage responses (DDR) to double-strand breaks (DSBs) alter cellular transcription programs at the genome-wide level. Through processes that are less well understood, DSBs also alter transcriptional responses locally, which...
4.
White B, Lanc I, ONeal J, Gupta H, Fulton R, Schmidt H, et al.
Blood Cancer J . 2018 Mar; 8(3):35. PMID: 29563506
Multiple myeloma (MM) is a disease of copy number variants (CNVs), chromosomal translocations, and single-nucleotide variants (SNVs). To enable integrative studies across these diverse mutation types, we developed a capture-based...