Harriet Wikman
Overview
Explore the profile of Harriet Wikman including associated specialties, affiliations and a list of published articles.
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Articles
97
Citations
3360
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Recent Articles
1.
Gotze J, Meissner K, Pereira-Veiga T, Belloum Y, Schneegans S, Kropidlowski J, et al.
J Exp Clin Cancer Res
. 2025 Jan;
44(1):14.
PMID: 39815324
Background: The lack of predictive biomarkers contributes notably to the poor outcomes of patients with pancreatic ductal adenocarcinoma (PDAC). Cancer-associated fibroblasts (CAFs) are the key components of the prominent PDAC...
2.
Gorgulho J, Loosen S, Masood R, Giehren F, Pagani F, Buescher G, et al.
J Exp Clin Cancer Res
. 2024 Nov;
43(1):298.
PMID: 39511626
Background: The major breakthrough in cancer therapy with immune checkpoint inhibitors (ICIs) has highlighted the important role of immune checkpoints in antitumoral immunity. However, most patients do not achieve durable...
3.
Nitschke C, Tolle M, Walter P, Meissner K, Goetz M, Kropidlowski J, et al.
Mol Oncol
. 2024 Sep;
PMID: 39219164
Intraductal papillary mucinous neoplasms (IPMNs) are potential precursor lesions of pancreatic cancer. We assessed the efficacy of screening for KRAS proto-oncogene, GTPase (KRAS), and GNAS complex locus (GNAS) mutations in...
4.
Goradia N, Werner S, Mullapudi E, Greimeier S, Bergmann L, Lang A, et al.
Nat Commun
. 2024 Jun;
15(1):5241.
PMID: 38898011
While the elucidation of regulatory mechanisms of folded proteins is facilitated due to their amenability to high-resolution structural characterization, investigation of these mechanisms in disordered proteins is more challenging due...
5.
Kruger K, Grust A, Muallah D, Patenge A, Wikman H, Mesa M, et al.
Anticancer Res
. 2024 May;
44(6):2369-2376.
PMID: 38821622
Background/aim: This study aimed at the analogous detection of PIK3CA mutations, common in oral squamous cell carcinoma (OSCC), in matched tumor and saliva samples. Patients And Methods: Tissue and saliva...
6.
Schneegans S, Loptien J, Mojzisch A, Loreth D, Kretz O, Raschdorf C, et al.
J Exp Clin Cancer Res
. 2024 Apr;
43(1):110.
PMID: 38605423
Background: Metastasis is the leading cause of cancer-related death in non-small cell lung cancer (NSCLC) patients. We previously showed that low HERC5 expression predicts early tumor dissemination and a dismal...
7.
Herbst J, Vohl V, Krajina M, Leffers M, Kropidlowski J, Prieske K, et al.
Clin Chem
. 2024 Jan;
70(1):285-296.
PMID: 38175596
Background: More than 95% of cervical cancers and their precancerous lesions are caused by human papillomavirus (HPV). Cell-free (cf) HPV DNA detection in blood samples may serve as a monitoring...
8.
Pouyiourou M, Bochtler T, Coith C, Wikman H, Kraft B, Hielscher T, et al.
Clin Chem
. 2024 Jan;
70(1):297-306.
PMID: 38175594
Background: Cancer of unknown primary (CUP) is defined as a primary metastatic malignancy, in which the primary tumor remains elusive in spite of a comprehensive diagnostic workup. The frequency and...
9.
Prokakis E, Jansari S, Boshnakovska A, Wiese M, Kusch K, Kramm C, et al.
Cell Death Dis
. 2023 Sep;
14(9):641.
PMID: 37770435
Triple-negative breast cancer (TNBC) is the most difficult breast cancer subtype to treat due to the lack of targeted therapies. Cancer stem cells (CSCs) are strongly enriched in TNBC lesions...
10.
van der Leest P, Janning M, Rifaela N, Azpurua M, Kropidlowski J, Loges S, et al.
Int J Mol Sci
. 2023 Sep;
24(17).
PMID: 37686200
Analysis of circulating tumor DNA (ctDNA) is a potential minimally invasive molecular tool to guide treatment decision-making and disease monitoring. A suitable diagnostic-grade platform is required for the detection of...