Harini Sadeeshkumar
Overview
Explore the profile of Harini Sadeeshkumar including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
8
Citations
319
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Sadeeshkumar H, Balaji A, Sutherland A, Mootien S, Anthony K, Breaker R
Anal Biochem
. 2023 Jan;
666:115047.
PMID: 36682579
Due to the emergence of multidrug resistant pathogens, it is imperative to identify new targets for antibiotic drug discovery. The S-adenosylhomocysteine (SAH) nucleosidase enzyme is a promising target for antimicrobial...
2.
White N, Sadeeshkumar H, Sun A, Sudarsan N, Breaker R
Sci Rep
. 2022 Nov;
12(1):19145.
PMID: 36352003
Lithium is rare in Earth's crust compared to the biologically relevant alkali metal cations sodium and potassium but can accumulate to toxic levels in some environments. We report the experimental...
3.
Sherlock M, Higgs G, Yu D, Widner D, White N, Sudarsan N, et al.
RNA Biol
. 2022 Sep;
19(1):1059-1076.
PMID: 36093908
Riboswitch architectures that involve the binding of a single ligand to a single RNA aptamer domain result in ordinary dose-response curves that require approximately a 100-fold change in ligand concentration...
4.
White N, Sadeeshkumar H, Sun A, Sudarsan N, Breaker R
Nat Chem Biol
. 2022 Jul;
18(8):878-885.
PMID: 35879547
Organisms presumably have mechanisms to monitor and physiologically adapt to changes in cellular Na concentrations. Only a single bacterial protein has previously been demonstrated to selectively sense Na and regulate...
5.
Sherlock M, Sadeeshkumar H, Breaker R
Biochemistry
. 2018 Aug;
58(5):401-410.
PMID: 30081631
The ykkC RNA motif was a long-standing orphan riboswitch candidate that has recently been proposed to encompass at least five distinct bacterial riboswitch classes. Most ykkC RNAs belong to the...
6.
Price M, Wetmore K, Waters R, Callaghan M, Ray J, Liu H, et al.
Nature
. 2018 May;
557(7706):503-509.
PMID: 29769716
One-third of all protein-coding genes from bacterial genomes cannot be annotated with a function. Here, to investigate the functions of these genes, we present genome-wide mutant fitness data from 32...
7.
Kulalert W, Sadeeshkumar H, Zhang Y, Schroeder F, Kim D
Genetics
. 2017 Mar;
206(1):251-263.
PMID: 28292919
Cell-nonautonomous effects of signaling in the nervous system of animals can influence diverse aspects of organismal physiology. We previously showed that phosphorylation of Ser49 of the α-subunit of eukaryotic translation...
8.
Pereira A, Lee D, Sadeeshkumar H, Laroche C, Odell D, Rempel D
Hum Factors
. 2013 Jul;
55(3):557-66.
PMID: 23829030
Objective: In this study, we evaluated the effects of key spacing on a conventional computer keyboard on typing speed, percentage error, usability, and forearm muscle activity and wrist posture. Background:...