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Harald Winter

Explore the profile of Harald Winter including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 416
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Recent Articles
1.
Kuhn S, Knirsch M, Ruttiger L, Kasperek S, Winter H, Freichel M, et al.
Channels (Austin) . 2009 Sep; 3(5):366-76. PMID: 19755851
Voltage-activated Ca(2+) channels comprise complexes of a pore-forming Ca(V)alpha(1) and auxiliary subunits Ca(V)beta, Ca(V)alpha(2)delta and sometimes Ca(V)gamma. The intracellular Ca(V)beta subunit assists in trafficking and surface expression of the Ca(V)alpha(1)...
2.
Winter H, Ruttiger L, Muller M, Kuhn S, Brandt N, Zimmermann U, et al.
J Neurosci . 2009 Feb; 29(8):2581-7. PMID: 19244534
Thyroid hormone receptor beta (TRbeta) dysfunction leads to deafness in humans and mice. Deafness in TRbeta(-/-) mutant mice has been attributed to TRbeta-mediated control of voltage- and Ca(2+)-activated K(+) (BK)...
3.
Quignodon L, Vincent S, Winter H, Samarut J, Flamant F
Mol Endocrinol . 2007 Jul; 21(10):2350-60. PMID: 17622582
Thyroid hormones act directly on transcription by binding to TRalpha1, TRbeta1, and TRbeta2 nuclear receptors, regulating many aspects of postnatal development and homeostasis. To analyze precisely the implication of the...
4.
Winter H, Braig C, Zimmermann U, Engel J, Rohbock K, Knipper M
Histochem Cell Biol . 2007 May; 128(1):65-75. PMID: 17520268
Cochlear outer hair cells (OHCs) terminally differentiate prior to the onset of hearing. During this time period, thyroid hormone (TH) dramatically influences inner ear development. It has been shown recently...
5.
Brandt N, Kuhn S, Munkner S, Braig C, Winter H, Blin N, et al.
J Neurosci . 2007 Mar; 27(12):3174-86. PMID: 17376979
Thyroid hormone (TH) is essential for the development of hearing. Lack of TH in a critical developmental period from embryonic day 17 to postnatal day 12 (P12) in rats and...
6.
Albert J, Winter H, Schaechinger T, Weber T, Wang X, He D, et al.
J Physiol . 2007 Feb; 580(Pt. 2):451-61. PMID: 17272340
Prestin, a member of the solute carrier (SLC) family SLC26A, is the molecular motor that drives the somatic electromotility of mammalian outer hair cells (OHCs). Its closest reported homologue, zebrafish...
7.
Schug N, Braig C, Zimmermann U, Engel J, Winter H, Ruth P, et al.
Eur J Neurosci . 2007 Jan; 24(12):3372-80. PMID: 17229086
Mutations of the human otoferlin gene lead to an autosomal recessive nonsyndromic form of prelingual, sensorineural deafness (deafness autosomal recessive 9, DFNB9). Several studies have demonstrated expression of otoferlin in...
8.
Knipper M, Weber T, Winter H, Braig C, Cimerman J, Fraenzer J, et al.
Novartis Found Symp . 2006 Nov; 273:19-30. PMID: 17120759
The 10-member SLC26 gene family encodes anion exchangers of which SLC26A5 appears to be restricted to the outer hair cells of the inner ear. Here, the so-called prestin protein acts...
9.
Winter H, Braig C, Zimmermann U, Geisler H, Franzer J, Weber T, et al.
J Cell Sci . 2006 Jun; 119(Pt 14):2975-84. PMID: 16803873
Thyroid hormone (TH or T3) and TH-receptor beta (TRbeta) have been reported to be relevant for cochlear development and hearing function. Mutations in the TRbeta gene result in deafness associated...
10.
Lowenheim H, Reichl J, Winter H, Hahn H, Simon C, Gultig K, et al.
Tissue Eng . 2005 Mar; 11(1-2):64-75. PMID: 15738662
In vitro expansion of chondrocytes for tissue-engineering applications is limited by forms of growth arrest known as quiescence and replicative senescence. At the molecular level cyclin-dependent kinase inhibitors (CDKIs) are...