Harald Nothaft
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Explore the profile of Harald Nothaft including associated specialties, affiliations and a list of published articles.
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44
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1378
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Recent Articles
1.
Fantone K, Nothaft H, Son Y, Stecenko A, Szymanski C, Rada B
Heliyon
. 2024 Oct;
10(19):e38895.
PMID: 39444402
Cystic Fibrosis (CF) airway disease is characterized by impaired mucociliary clearance, chronic, polymicrobial infections and robust, neutrophil-dominated inflammation. Pulmonary disease is the leading cause of morbidity and mortality in people...
2.
Nothaft H, Perez-Munoz M, Yang T, Murugan A, Miller M, Kolarich D, et al.
Front Microbiol
. 2021 Dec;
12:734526.
PMID: 34867850
is a common cause of diarrheal disease worldwide. Human infection typically occurs through the ingestion of contaminated poultry products. We previously demonstrated that an attenuated live vaccine strain expressing the...
3.
Nothaft H, Bian X, Shajahan A, Miller W, Bolick D, Guerrant R, et al.
ACS Chem Biol
. 2021 Nov;
16(11):2690-2701.
PMID: 34726367
is a significant cause of human gastroenteritis worldwide, and all strains express an N-glycan that is added to at least 80 different proteins. We characterized 98 isolates from infants from...
4.
Thomas C, Nothaft H, Yadav R, Fodor C, Alemka A, Oni O, et al.
PLoS One
. 2020 Dec;
15(12):e0244031.
PMID: 33378351
Ecotin, first described in Escherichia coli, is a potent inhibitor of a broad range of serine proteases including those typically released by the innate immune system such as neutrophil elastase...
5.
Duma J, Nothaft H, Weaver D, Fodor C, Beadle B, Linton D, et al.
Front Microbiol
. 2020 Jul;
11:1191.
PMID: 32625174
is commonly associated with venereal disease and abortions in cattle and sheep, and can also cause intestinal or systemic infections in humans that are immunocompromised, elderly, or exposed to infected...
6.
Wenzel C, Mills D, Dobruchowska J, Vlach J, Nothaft H, Nation P, et al.
J Biol Chem
. 2020 May;
295(28):9513-9530.
PMID: 32424044
is a leading cause of food-poisoning and causes avian necrotic enteritis, posing a significant problem to both the poultry industry and human health. No effective vaccine against is currently available....
7.
Nothaft H, Scott N, Vinogradov E, Liu X, Hu R, Beadle B, et al.
Mol Cell Proteomics
. 2020 May;
19(5):913.
PMID: 32358173
No abstract available.
8.
Garber J, Nothaft H, Pluvinage B, Stahl M, Bian X, Porfirio S, et al.
Commun Biol
. 2020 Jan;
3(1):2.
PMID: 31925306
Although the gastrointestinal pathogen Campylobacter jejuni was considered asaccharolytic, >50% of sequenced isolates possess an operon for L-fucose utilization. In C. jejuni NCTC11168, this pathway confers L-fucose chemotaxis and competitive...
9.
Dubb R, Nothaft H, Beadle B, Richards M, Szymanski C
Glycobiology
. 2019 Oct;
30(2):105-119.
PMID: 31588498
Campylobacter jejuni is a prevalent gastrointestinal pathogen associated with increasing rates of antimicrobial resistance development. It was also the first bacterium demonstrated to possess a general N-linked protein glycosylation pathway...
10.
Nothaft H, Szymanski C
Curr Opin Chem Biol
. 2019 Jul;
53:16-24.
PMID: 31288139
Historically, protein glycosylation was believed to be restricted to eukaryotes, but now is abundantly represented in all three domains of life. The first bacterial N-linked glycosylation system was discovered in...