Haojun Chen
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Explore the profile of Haojun Chen including associated specialties, affiliations and a list of published articles.
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126
Citations
1637
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Recent Articles
1.
Fu H, Huang J, Zhao L, Chen Y, Xu W, Cai J, et al.
Clin Cancer Res
. 2025 Mar;
:OF1-OF12.
PMID: 40084923
Purpose: Fibroblast activation protein (FAP) is highly expressed in cancer-associated fibroblasts and certain tumor cells, making it a promising therapeutic target for various malignancies. This study evaluated the efficacy and...
2.
Sun Y, Hao Z, Gao H, Yang G, Pan B, Zhu M, et al.
J Nucl Med
. 2025 Feb;
PMID: 39947911
The trophoblast cell-surface antigen 2 (Trop2) is markedly overexpressed in breast cancers, with a particularly high incidence in triple-negative breast cancer. The therapeutic relevance of Trop2 expression is underscored by...
3.
Guo W, Xu W, Meng T, Fan C, Fu H, Pang Y, et al.
Eur J Nucl Med Mol Imaging
. 2025 Jan;
PMID: 39883140
Purpose: To evaluate the diagnostic accuracy and clinical impact of fibroblast activation protein (FAP)-targeted PET/CT imaging in primary and metastatic breast cancer and compare the results with those of standard-of-care...
4.
Zhu D, Song S, Zou S, Kuang D, Wang D, Min X, et al.
Eur J Nucl Med Mol Imaging
. 2025 Jan;
PMID: 39831967
Purpose: To investigate the efficacy of [Ga]Ga-FAPI-04 PET/CT for assessing viable tumours (VTs) after local regional treatment (LRT) in hepatocellular carcinoma (HCC) patients. The related imaging features of HCC after...
5.
Chen J, Zhou Y, Pang Y, Fu K, Luo Q, Sun L, et al.
J Immunother Cancer
. 2025 Jan;
13(1.
PMID: 39800373
Background: Fibroblast activation protein (FAP)-targeted radioligand therapy, with immunomodulatory effects, has shown efficacy in both preclinical and clinical studies. We recently reported on a novel dimeric FAP-targeting radiopharmaceutical, Ga/Lu-DOTA-2P(FAPI), which...
6.
Ruan D, Wu S, Lin X, Zhao L, Cai J, Xu W, et al.
Biophys Rep
. 2025 Jan;
10(6):388-402.
PMID: 39758423
Fibroblast activation protein (FAP) is a key molecule in the field of oncology, with significant impacts on tumor diagnosis and treatment. Importantly, it has paved the way for the development...
7.
Ruan D, Sun J, Han C, Cai J, Yu L, Zhao L, et al.
Theranostics
. 2024 Dec;
14(18):6935-6946.
PMID: 39629119
This study compared Ga-FAPI-46 PET/CT, F-fluorodeoxyglucose (FDG) PET/CT, and contrast-enhanced MRI (CE-MRI) for glioma imaging, classification, and recurrence detection and explored PET parameters and molecular pathological profiles. Between June 2020...
8.
Chen H, Zhao L, Pang Y, Shi J, Gao H, Sun Y, et al.
J Clin Invest
. 2024 Nov;
135(1).
PMID: 39509246
BACKGROUNDConsidering that trophoblast cell-surface antigen 2 (Trop2) is overexpressed in a wide range of human epithelial cancers, it presents an attractive target for diagnosis and treatment of multiple types of...
9.
Fu K, Zhao L, Cai J, Yu L, Chen H
Clin Nucl Med
. 2024 Oct;
49(12):1159-1161.
PMID: 39354687
Solitary fibrous tumors (SFTs) are fibroblast tumors that occur mainly in the pleura. Hepatic SFT with skeleton metastases was rarely documented. In this case, we report the contrast-enhanced CT, 18...
10.
Chen J, Pang Y, Liao X, Zhou Y, Luo Q, Wu H, et al.
Eur J Nucl Med Mol Imaging
. 2024 Aug;
52(1):247-259.
PMID: 39145784
Purpose: Somatostatin Receptor 2 (SSTR2)-targeted radiopharmaceutical [Ga]Ga-DOTATATE has potential advantages in the diagnosis of nasopharyngeal carcinoma (NPC). This study introduces a novel long-lasting SSTR2 analogue, LNC1010, based on DOTATATE, a...