Hans Jornvall
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Explore the profile of Hans Jornvall including associated specialties, affiliations and a list of published articles.
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132
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2516
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Recent Articles
11.
Landreh M, Rising A, Presto J, Jornvall H, Johansson J
J Biol Chem
. 2015 Sep;
290(44):26430-6.
PMID: 26354437
Many proteins can form amyloid-like fibrils in vitro, but only about 30 amyloids are linked to disease, whereas some proteins form physiological amyloid-like assemblies. This raises questions of how the...
12.
Naseeb U, Axelsson J, Jagerbrink T, Shafqat J, Zarina S, Jornvall H
J Coll Physicians Surg Pak
. 2015 Aug;
25(8):606-9.
PMID: 26305309
Objective: To complement an earlier analysis of protein alterations in plasma from uremic versus healthy subjects by addition of further LC-MS/MS analysis to the previously used MALDI-TOF mass analyses. Methodology:...
13.
Otikovs M, Chen G, Nordling K, Landreh M, Meng Q, Jornvall H, et al.
Chembiochem
. 2015 Jun;
16(12):1720-4.
PMID: 26033527
Conversion of spider silk proteins from soluble dope to insoluble fibers involves pH-dependent dimerization of the N-terminal domain (NT). This conversion is tightly regulated to prevent premature precipitation and enable...
14.
Landreh M, Jornvall H
FEBS Lett
. 2015 Jan;
589(4):415-8.
PMID: 25595456
The proinsulin C-peptide has molecular, cellular and organismal activities but lacks disease-associated mutations or short-term loss-of-function effects. This dilemma between activity and function may be explained from its evolutionary setting...
15.
Jornvall H, Landreh M, Ostberg L
Chem Biol Interact
. 2014 Dec;
234:75-9.
PMID: 25451589
It is now about half a century since molecular research on alcohol dehydrogenase (ADH), short-chain dehydrogenase/reductase (SDR) and medium-chain dehydrogenase/reductase (MDR) started. During this time, at least four stages of...
16.
Landreh M, Ostberg L, Pettersson T, Jornvall H
Biomol Concepts
. 2014 Nov;
5(3):257-64.
PMID: 25372757
Aggregation of transthyretin (TTR), a plasma-binding protein for thyroxine and retinol-binding protein, is the cause of several amyloid diseases. Disease-associated mutations are well known, but wild-type TTR is, to a...
17.
Landreh M, Johansson J, Wahren J, Jornvall H
Biomol Concepts
. 2014 Nov;
5(2):109-18.
PMID: 25372746
Many biological roles have been assigned to proinsulin C-peptide over the years. Some appear surprisingly disparate and sometimes even contradictory, like chaperone-like actions and depository tendencies. This review summarizes recently...
18.
Andersson M, Chen G, Otikovs M, Landreh M, Nordling K, Kronqvist N, et al.
PLoS Biol
. 2014 Aug;
12(8):e1001921.
PMID: 25093327
Spider silk fibers are produced from soluble proteins (spidroins) under ambient conditions in a complex but poorly understood process. Spidroins are highly repetitive in sequence but capped by nonrepetitive N-...
19.
Landreh M, Ostberg L, Jornvall H
Biochem Biophys Res Commun
. 2014 Jul;
450(4):1433-8.
PMID: 25017908
The C-peptide of proinsulin exhibits multiple activities and several of the underlying molecular interactions are known. We recently showed that human C-peptide is sub-divided into a tripartite architecture and that...
20.
Landreh M, Alvelius G, Johansson J, Jornvall H
Anal Chem
. 2014 Apr;
86(9):4135-9.
PMID: 24754426
Electrospray ionization mass spectrometry is a valuable tool to probe noncovalent interactions. However, the integrity of the interactions in the gas-phase is heavily influenced by the ionization process. Investigating oligomerization...