Hans-Martin Maischein
Overview
Explore the profile of Hans-Martin Maischein including associated specialties, affiliations and a list of published articles.
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32
Citations
1052
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Recent Articles
1.
Jiang Z, El-Brolosy M, Serobyan V, Welker J, Retzer N, Dooley C, et al.
Sci Adv
. 2022 Nov;
8(47):eabj2029.
PMID: 36427314
Transgenerational epigenetic inheritance (TEI) is mostly discussed in the context of physiological or environmental factors. Here, we show intergenerational and transgenerational inheritance of transcriptional adaptation (TA), a process whereby mutant...
2.
Yang Y, Briant L, Raab C, Mullapudi S, Maischein H, Kawakami K, et al.
Elife
. 2022 Apr;
11.
PMID: 35373736
The importance of pancreatic endocrine cell activity modulation by autonomic innervation has been debated. To investigate this question, we established an in vivo imaging model that also allows chronic and...
3.
Gentile A, Bensimon-Brito A, Priya R, Maischein H, Piesker J, Guenther S, et al.
Elife
. 2021 Jun;
10.
PMID: 34152269
The transcription factor Snai1, a well-known regulator of epithelial-to-mesenchymal transition, has been implicated in early cardiac morphogenesis as well as in cardiac valve formation. However, a role for Snai1 in...
4.
Priya R, Allanki S, Gentile A, Mansingh S, Uribe V, Maischein H, et al.
Nature
. 2020 Nov;
588(7836):130-134.
PMID: 33208950
How diverse cell fates and complex forms emerge and feed back to each other to sculpt functional organs remains unclear. In the developing heart, the myocardium transitions from a simple...
5.
Helker C, Eberlein J, Wilhelm K, Sugino T, Malchow J, Schuermann A, et al.
Elife
. 2020 Sep;
9.
PMID: 32955436
To form new blood vessels (angiogenesis), endothelial cells (ECs) must be activated and acquire highly migratory and proliferative phenotypes. However, the molecular mechanisms that govern these processes are incompletely understood....
6.
Fukuda R, Aharonov A, Ong Y, Stone O, El-Brolosy M, Maischein H, et al.
Elife
. 2019 Dec;
8.
PMID: 31868165
During cardiac development, cardiomyocytes form complex inner wall structures called trabeculae. Despite significant investigation into this process, the potential role of metabolism has not been addressed. Using single cell resolution...
7.
Villasenor A, Gauvrit S, Collins M, Maischein H, Stainier D
Dev Biol
. 2019 Nov;
458(2):228-236.
PMID: 31697936
Significant efforts have advanced our understanding of foregut-derived organ development; however, little is known about the molecular mechanisms that underlie the formation of the hepatopancreatic ductal (HPD) system. Here, we...
8.
Fukuda R, Gunawan F, Ramadass R, Beisaw A, Konzer A, Mullapudi S, et al.
Dev Cell
. 2019 Sep;
51(1):62-77.e5.
PMID: 31495694
Mechanical forces regulate cell behavior and tissue morphogenesis. During cardiac development, mechanical stimuli from the heartbeat are required for cardiomyocyte maturation, but the underlying molecular mechanisms remain unclear. Here, we...
9.
Rasouli S, El-Brolosy M, Tsedeke A, Bensimon-Brito A, Ghanbari P, Maischein H, et al.
Elife
. 2018 Dec;
7.
PMID: 30592462
Complex interplay between cardiac tissues is crucial for their integrity. The flow responsive transcription factor KLF2, which is expressed in the endocardium, is vital for cardiovascular development but its exact...
10.
Mullapudi S, Helker C, Boezio G, Maischein H, Sokol A, Guenther S, et al.
Elife
. 2018 Dec;
7.
PMID: 30520733
Pathways modulating glucose homeostasis independently of insulin would open new avenues to combat insulin resistance and diabetes. Here, we report the establishment, characterization, and use of a vertebrate 'insulin-free' model...