Andrea Bredemeyer
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Explore the profile of Andrea Bredemeyer including associated specialties, affiliations and a list of published articles.
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22
Citations
1314
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Recent Articles
1.
Amrute J, Lee P, Eres I, Lee C, Bredemeyer A, Sheth M, et al.
medRxiv
. 2024 Nov;
PMID: 39606421
Although genome wide association studies (GWAS) in large populations have identified hundreds of variants associated with common diseases such as coronary artery disease (CAD), most disease-associated variants lie within non-coding...
2.
Iglesia M, Jayasinghe R, Chen S, Terekhanova N, Herndon J, Storrs E, et al.
Nat Cancer
. 2024 Oct;
5(11):1713-1736.
PMID: 39478117
Breast cancer (BC) is defined by distinct molecular subtypes with different cells of origin. The transcriptional networks that characterize the subtype-specific tumor-normal lineages are not established. In this work, we...
3.
Amrute J, Luo X, Penna V, Yang S, Yamawaki T, Hayat S, et al.
Nature
. 2024 Oct;
635(8038):423-433.
PMID: 39443792
Inflammation and tissue fibrosis co-exist and are causally linked to organ dysfunction. However, the molecular mechanisms driving immune-fibroblast cell communication in human cardiac disease remain unexplored and there are at...
4.
Lou L, Detering L, Luehmann H, Amrute J, Sultan D, Ma P, et al.
Circ Res
. 2024 Sep;
135(10):990-1003.
PMID: 39328090
Background: Immune checkpoint inhibitor (ICI) usage has resulted in immune-related adverse events in patients with cancer, such as accelerated atherosclerosis. Of immune cells involved in atherosclerosis, the role of CCR2+...
5.
Dmytrenko O, Das S, Kovacs A, Cicka M, Liu M, Scheaffer S, et al.
J Virol
. 2024 Aug;
98(9):e0117924.
PMID: 39207134
Cardiovascular manifestations of coronavirus disease 2019 (COVID-19) include myocardial injury, heart failure, and myocarditis and are associated with long-term disability and mortality. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA...
6.
Zhang X, Heo G, Li A, Lahad D, Detering L, Tao J, et al.
J Nucl Med
. 2024 Mar;
65(5):775-780.
PMID: 38548349
Tissue-resident macrophages are complementary to proinflammatory macrophages to promote the progression of atherosclerosis. The noninvasive detection of their presence and dynamic variation will be important to the understanding of their...
7.
Iglesia M, Jayasinghe R, Chen S, Terekhanova N, Herndon J, Storrs E, et al.
bioRxiv
. 2023 Nov;
PMID: 37961519
Breast cancer is a heterogeneous disease, and treatment is guided by biomarker profiles representing distinct molecular subtypes. Breast cancer arises from the breast ductal epithelium, and experimental data suggests breast...
8.
Ma P, Liu J, Qin J, Lai L, Heo G, Luehmann H, et al.
Circulation
. 2023 Sep;
149(1):48-66.
PMID: 37746718
Background: Immune checkpoint inhibitors (ICIs), antibodies targeting PD-1 (programmed cell death protein 1)/PD-L1 (programmed death-ligand 1) or CTLA4 (cytotoxic T-lymphocyte-associated protein 4), have revolutionized cancer management but are associated with...
9.
Amrute J, Lai L, Ma P, Koenig A, Kamimoto K, Bredemeyer A, et al.
Nat Cardiovasc Res
. 2023 Aug;
2(4):399-416.
PMID: 37583573
Recovery of cardiac function is the holy grail of heart failure therapy yet is infrequently observed and remains poorly understood. In this study, we performed single-nucleus RNA sequencing from patients...
10.
Ma P, Liu J, Qin J, Lai L, Heo G, Luehmann H, et al.
bioRxiv
. 2023 May;
PMID: 37162929
Background: Immune checkpoint inhibitors (ICIs), antibodies targeting PD-1/PD-L1 or CTLA4 have revolutionized cancer management but are associated with devastating immune-related adverse events (irAEs) including myocarditis. The main risk factor for...