Hana Im
Overview
Explore the profile of Hana Im including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
245
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Recent Articles
1.
Kim B, Kim T, Im H, Shin K, Kang S
Biochem Biophys Res Commun
. 2024 Dec;
742:151157.
PMID: 39672006
A longevity factor α-Klotho has been shown to be neuroprotective and enhance brain function. However, it has not been elucidated whether α-Klotho is involved in the embryonic brain development. To...
2.
Lee I, Kim C, Cho H, Im H, Shin K, Kang S
Biochem Biophys Res Commun
. 2022 Aug;
627:97-102.
PMID: 36030658
A nuclear serine/threonine kinase homeodomain-interacting protein kinase 2 (HIPK2) is a critical regulator of development and DNA damage response. HIPK2 can induce apoptosis under cellular stress conditions and thus its...
3.
Im H, Lim J
Protein Pept Lett
. 2022 Mar;
29(5):384-391.
PMID: 35319354
Background: The Z-type variant of human α-antitrypsin is involved in liver cirrhosis and pulmonary emphysema. Due to its slow folding characteristics, this variant accumulates folding intermediates and forms protein aggregates...
4.
Jung Y, Uh J, Lee K, Im H
Biochem Biophys Res Commun
. 2018 Jan;
496(2):374-380.
PMID: 29330047
Organisms living in extremely cold environments possess mechanisms to survive low temperatures. Among the known cold-induced genes, cold-shock proteins (Csps) are the most prominent. A csp-homologous gene, cspB, has been...
5.
Jung Y, Lee Y, Lee H, Lee K, Im H
Braz J Microbiol
. 2017 Aug;
49(1):97-103.
PMID: 28807609
Freezing temperatures are a major challenge for life at the poles. Decreased membrane fluidity, uninvited secondary structure formation in nucleic acids, and protein cold-denaturation all occur at cold temperatures. Organisms...
6.
Kim H, Ra H, Kim K, Lee J, Im H, Kim Y
Mol Cells
. 2015 Mar;
38(4):312-7.
PMID: 25813624
Depletion of intracellular zinc by N,N,N',N'-tetrakis(2-pyridylmethyl) ethylenediamine (TPEN) induces p53-mediated protein synthesis-dependent apoptosis of mouse cortical neurons. Here, we examined the requirement for poly(ADP-ribose) polymerase (PARP)-1 as an upstream regulator...
7.
Lee J, Lee J, Kim K, Im H, Kim Y
Biochem Biophys Res Commun
. 2015 Feb;
459(2):220-226.
PMID: 25712525
During brain ischemic preconditioning (PC), mild bursts of ischemia render neurons resistant to subsequent strong ischemic injuries. Previously, we reported that zinc plays a key role in PC-induced neuroprotection in...
8.
Jung C, Kim Y, Lee K, Im H
Biochem Biophys Res Commun
. 2014 Feb;
445(1):191-5.
PMID: 24502947
The human Z-type α1-antitrypsin variant has a strong tendency to accumulate folding intermediates due to extremely slow protein folding within the endoplasmic reticulum (ER) of hepatocytes. Human α1-antitrypsin has 17...
9.
Naicker M, Seul Jo I, Im H
J Microbiol
. 2012 Nov;
50(5):882-7.
PMID: 23124761
Exposure to low temperatures reduces protein folding rates and induces the cold denaturation of proteins. Considering the roles played by chaperones in facilitating protein folding and preventing protein aggregation, chaperones...
10.
Lee H, Lee K, Im H
Biochem Biophys Res Commun
. 2012 Jul;
424(3):497-502.
PMID: 22771809
α-Synuclein is the major component of Lewy bodies and Lewy neurites, the pathological hallmarks of surviving neuronal cells in Parkinson's disease patients. However, the physiological role played by α-synuclein remains...