Yu-Ran Na
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Explore the profile of Yu-Ran Na including associated specialties, affiliations and a list of published articles.
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13
Citations
89
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Recent Articles
1.
Chang S, Song D, Oh S, Han S, Jung J, Song N, et al.
Eur J Pharm Sci
. 2024 May;
199:106820.
PMID: 38821248
Obesity is a global public health problem and is related with fatal diseases such as cancer and cardiovascular and metabolic diseases. Medical and lifestyle-related strategies to combat obesity have their...
2.
Na Y, Woo D, Kim S, Yang E
Biochem Biophys Res Commun
. 2016 Mar;
472(2):313-8.
PMID: 26940742
Increasing evidence emphasizes the role of the hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) isoforms in regulating non-HIF substrates, but isoform selective PHD inhibitors under physiological conditions have not yet been...
3.
Kim H, Na Y, Kim S, Yang E
J Cell Biochem
. 2015 Aug;
117(3):647-58.
PMID: 26284819
Hypoxia-inducible factor-1α (HIF-1α) is one of the key transcription factors that mediate adaptation to hypoxia. Despite increasing evidence implicating the PKC family as potential modulators of HIF-1α, the molecular mechanisms...
4.
Na Y, Woo D, Choo H, Chung H, Yang E
Chem Commun (Camb)
. 2015 Jun;
51(53):10730-3.
PMID: 26051901
We report herein that Zn(II) selectively inhibits the hypoxia-inducible factor prolyl hydroxylase PHD3 over PHD2, and does not compete with Fe(II). Independent of the oligomer formation induced by Zn(II), inhibition...
5.
Kim S, Lee M, Na Y, Kim S, Yang E
J Cell Biochem
. 2013 Aug;
115(2):271-80.
PMID: 23966271
Hypoxia-inducible factor (HIF)-1α mediates the hypoxia response signaling pathway essential for maintaining cellular homeostasis in low oxygen environments through its complex formation with CBP/p300 in the nucleus. Employing fluorescence resonance...
6.
Na Y, Han K, Park H, Yang E
Biochem Biophys Res Commun
. 2013 Apr;
434(4):879-84.
PMID: 23618863
Hypoxia is a general characteristic of most solid malignancies and intimately related to neoplastic diseases and cancer progression. Homeostatic response to hypoxia is primarily mediated by hypoxia inducible factor (HIF)-1α...
7.
Na Y, Kim S, Gaublomme J, Shalek A, Jorgolli M, Park H, et al.
Nano Lett
. 2012 Dec;
13(1):153-8.
PMID: 23244056
Developing a detailed understanding of enzyme function in the context of an intracellular signal transduction pathway requires minimally invasive methods for probing enzyme activity in situ. Here, we describe a...
8.
Kim S, Lee M, Kim J, Na Y, Lee H, Cho H, et al.
Biol Pharm Bull
. 2012 Dec;
35(12):2160-9.
PMID: 23207768
We previously found that clioquinol (CQ) increases functional hypoxia-inducible factor-1α (HIF-1α) with enhanced transcription of its target genes. Here we report that compounds derived from 8-hydroxyquinoline including CQ, broxyquinoline (BQ),...
9.
Na Y, Park C
Protein Sci
. 2009 Jan;
18(2):268-76.
PMID: 19177560
Investigation of protein unfolding kinetics of proteins in crude samples may provide many exciting opportunities to study protein energetics under unconventional conditions. As an effort to develop a method with...
10.
Na Y, Im H
Protein Sci
. 2007 Jun;
16(8):1659-66.
PMID: 17600149
Plasminogen activator inhibitor-1 (PAI-1) belongs to the serine protease inhibitor (serpin) protein superfamily. Serpins are unique in that their native forms are not the most thermodynamically stable conformation; instead, a...