Hajime Nishimura
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Explore the profile of Hajime Nishimura including associated specialties, affiliations and a list of published articles.
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22
Citations
289
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Recent Articles
1.
Xu Y, Mishra H, Furutani Y, Yanaka K, Nishimura H, Furuhata E, et al.
Front Oncol
. 2025 Mar;
15:1486671.
PMID: 40027135
MYCN, an oncogene implicated in hepatocellular carcinoma (HCC), is predominantly expressed in cancer stem-like HCC cells. It drives tumorigenicity, metastasis, and therapeutic resistance. In this study, we hypothesized that the...
2.
Yoshida M, Kwon A, Qin X, Nishimura H, Maeda S, Miyamoto Y, et al.
Front Immunol
. 2024 May;
15:1374437.
PMID: 38711507
complex (MAC) is a non-tuberculous mycobacterium widely distributed in the environment. Even though MAC infection is increasing in older women and immunocompromised patients, to our knowledge there has been no...
3.
Suzuki T, Furuhata E, Maeda S, Kishima M, Miyajima Y, Tanaka Y, et al.
Commun Biol
. 2022 May;
5(1):414.
PMID: 35508708
Hepatocytes are the dominant cell type in the human liver, with functions in metabolism, detoxification, and producing secreted proteins. Although gene regulation and master transcription factors involved in the hepatocyte...
4.
Miyajima Y, Noguchi S, Tanaka Y, Li J, Nishimura H, Kishima M, et al.
Chromosome Res
. 2022 Feb;
30(1):109-121.
PMID: 35142952
DNA methylation of CpG dinucleotides is an important epigenetic modification involved in the regulation of mammalian gene expression, with each type of cell developing a specific methylation profile during its...
5.
Abe T, Nishimura H, Sato T, Suzuki H, Ogawa T, Suzuki T
Data Brief
. 2020 Nov;
33:106482.
PMID: 33241095
spermatogenesis, which produces fertile spermatozoa, has been successfully performed using an organ culture method from murine tissue. Here, we provide a dataset of time-course microarray transcriptome data of cultured neonate...
6.
Abe T, Nishimura H, Sato T, Suzuki H, Ogawa T, Suzuki T
Biochem Biophys Res Commun
. 2020 Aug;
530(4):732-738.
PMID: 32782148
Cultivation of neonatal mouse testis tissue can induce spermatogenesis and produce fertile sperms. However, in vitro spermatogenesis mediated by the current organ culture method comes short in fully mimicking the...
7.
Watanabe K, Liu Y, Noguchi S, Murray M, Chang J, Kishima M, et al.
Sci Rep
. 2019 Apr;
9(1):6490.
PMID: 31019211
Mesenchymal-to-epithelial transition (MET) is an important step in cell reprogramming from fibroblasts (a cell type frequently used for this purpose) to various epithelial cell types. However, the mechanism underlying MET...
8.
Nakagawa S, Nishimura H, Kodera F
Anal Sci
. 2018 Jan;
34(1):1-4.
PMID: 29321448
In this study, we developed a new chlorine gas detection method using anodic oxidation and a photochemical reaction. Chlorine gas was temporarily solvated with an aprotic polar solvent having an...
9.
Suzuki T, Shimizu Y, Furuhata E, Maeda S, Kishima M, Nishimura H, et al.
Blood Adv
. 2018 Jan;
1(20):1699-1711.
PMID: 29296817
RUNX1 is an essential master transcription factor in hematopoietic development and plays important roles in immune functions. Although the gene regulatory mechanism of RUNX1 has been characterized extensively, the epigenetic...
10.
Suzuki T, Maeda S, Furuhata E, Shimizu Y, Nishimura H, Kishima M, et al.
Epigenetics Chromatin
. 2017 Dec;
10(1):60.
PMID: 29221486
Background: DNA methylation is a fundamental epigenetic modification that is involved in many biological systems such as differentiation and disease. We and others recently showed that some transcription factors (TFs)...