Haizhong Zhu
Overview
Explore the profile of Haizhong Zhu including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
26
Citations
575
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0
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Recent Articles
1.
Ramos A, Goedken E, Frank K, Argiriadi M, Bazzaz S, Bian Z, et al.
J Med Chem
. 2024 Apr;
67(8):6456-6494.
PMID: 38574366
Dysregulation of IL17A drives numerous inflammatory and autoimmune disorders with inhibition of IL17A using antibodies proven as an effective treatment. Oral anti-IL17 therapies are an attractive alternative option, and several...
2.
Hobson A, Zhu H, Qiu W, Judge R, Longenecker K
RSC Med Chem
. 2024 Mar;
15(3):1072.
PMID: 38516596
[This corrects the article DOI: 10.1039/D3MD00540B.].
3.
Hobson A, Zhu H, Qiu W, Judge R, Longenecker K
RSC Med Chem
. 2024 Mar;
15(3):832-838.
PMID: 38516584
Glucocorticoid receptor modulators (GRMs) are an established and successful compound class for the treatment of multiple diseases. In addition, they are an area of high interest as payloads for antibody-drug...
4.
Plotnik J, Richardson A, Yang H, Rojas E, Bontcheva V, Dowell C, et al.
Mol Cancer Ther
. 2024 Mar;
23(7):949-960.
PMID: 38507740
The activated B cell (ABC) subset of diffuse large B-cell lymphoma (DLBCL) is characterized by chronic B-cell receptor signaling and associated with poor outcomes when treated with standard therapy. In...
5.
McPherson M, Hobson A, Hernandez Jr A, Marvin C, Waegell W, Goess C, et al.
Sci Transl Med
. 2024 Mar;
16(739):eadd8936.
PMID: 38507467
Glucocorticoids (GCs) are efficacious drugs used for treating many inflammatory diseases, but the dose and duration of administration are limited because of severe side effects. We therefore sought to identify...
6.
Zhang Z, Yang X, Zhang L, Zhu H, Huang B, Chen Q, et al.
Bioanalysis
. 2023 Apr;
15(7):371-390.
PMID: 37057990
Sodium oligomannate was approved for marketing by the National Medical Products Administration of China in 2019 for improving cognitive functions in mild-to-moderate Alzheimer's disease patients. LC-MS/MS methods were established and...
7.
Goedken E, Argiriadi M, Dietrich J, Petros A, Krishnan N, Panchal S, et al.
Sci Rep
. 2022 Aug;
12(1):14561.
PMID: 36028520
Anti-IL17A therapies have proven effective for numerous inflammatory diseases including psoriasis, axial spondylitis and psoriatic arthritis. Modulating and/or antagonizing protein-protein interactions of IL17A cytokine binding to its cell surface receptors...
8.
Walker B, Tempel W, Zhu H, Park H, Cochran J
Biochemistry
. 2019 Apr;
58(18):2326-2338.
PMID: 30973712
Chromokinesins NOD and KID have similar DNA binding domains and functions during cell division, while their motor domain sequences show significant variations. It has been unclear whether these motors have...
9.
Nawaz M, Ferreira J, Nedyalkova L, Zhu H, Carrasco-Lopez C, Kirmizialtin S, et al.
Biosci Rep
. 2018 Jan;
38(1).
PMID: 29298880
The high proliferation rate of tumor cells demands high energy and metabolites that are sustained by a high glycolytic flux known as the 'Warburg effect'. The activation and further metabolism...
10.
Park H, Ma Z, Zhu H, Jiang S, Robinson R, Endow S
Sci Rep
. 2017 Nov;
7(1):15121.
PMID: 29123223
Kinesin microtubule motor proteins play essential roles in division, including attaching chromosomes to spindles and crosslinking microtubules for spindle assembly. Human kinesin-14 KIFC1 is unique in that cancer cells with...