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Hailong Ou

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Articles 19
Citations 151
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Recent Articles
1.
He H, Jiang T, Ding M, Zhu Y, Xu X, Huang Y, et al.
Redox Biol . 2024 Dec; 79():103477. PMID: 39721498
NADPH oxidase 1 (Nox1) is a major isoform of Nox in vascular smooth muscle cells (VSMCs). VSMC activation and extracellular matrix (ECM) remodelling induce abdominal aortic aneurysm (AAA). In this...
2.
Ding M, Zhu Y, Xu X, He H, Jiang T, Mo X, et al.
J Agric Food Chem . 2024 Mar; 72(13):7130-7139. PMID: 38516841
Macrophage inflammation and oxidative stress promote atherosclerosis progression. Naringenin is a naturally occurring flavonoid with antiatherosclerotic properties. Here, we elucidated the effects of naringenin on monocyte/macrophage endothelial infiltration and vascular...
3.
Liu Y, Li J, Ou H, Qi D, Hu B, Xu Y, et al.
Genes Dis . 2023 Jul; 10(5):2137-2150. PMID: 37492709
Aptamers, short single DNA or RNA oligonucleotides, have shown immense application potential as molecular probes for the early diagnosis and therapy of cancer. However, conventional cell-SELEX technologies for aptamer discovery...
4.
Liu Y, Hu B, Pei X, Li J, Qi D, Xu Y, et al.
Adv Healthc Mater . 2023 Jun; 12(20):e2300791. PMID: 37262080
Bladder cancer (BC) is a highly aggressive malignant tumor affecting the urinary system, characterized by metastasis and a poor prognosis that often leads to limited therapeutic success. This study aims...
5.
Zhou S, Ou H, Wu Y, Qi D, Pei X, Yu X, et al.
Pharmacol Ther . 2023 May; 247:108434. PMID: 37172786
Tumor endothelial cells (TECs) reside in the inner lining of blood vessels and represent a promising target for targeted cancer therapy. DNA methylation is a chemical process that involves the...
6.
Zhang Y, Dong D, Xu X, He H, Zhu Y, Lei T, et al.
J Biol Chem . 2022 May; 298(6):102000. PMID: 35500650
Oxidized high-density lipoprotein (oxHDL) reduces the ability of cells to mediate reverse cholesterol transport and also shows atherogenic properties. Palmitoylation of cluster of differentiation 36 (CD36), an important receptor mediating...
7.
Dong D, Zhang Y, He H, Zhu Y, Ou H
FASEB J . 2022 Mar; 36(4):e22261. PMID: 35332570
Alpinetin is a plant flavonoid isolated from Alpinia katsumadai Hayata with antioxidant and anti-inflammatory properties. Monocyte infiltration into the intima promotes atherosclerotic development and causes plaque instability at the later...
8.
Liu Y, Peng C, Zhang H, Li J, Ou H, Sun Y, et al.
Bioact Mater . 2022 Mar; 12:278-291. PMID: 35310383
Fibrosarcoma is a serious malignant mesenchymal tumor with strong invasiveness, high recurrence, and poor prognosis. Currently, surgical resection is the main treatment for fibrosarcoma. However, due to the lack of...
9.
Li W, Xu X, Dong D, Lei T, Ou H
Free Radic Biol Med . 2020 Nov; 162:542-554. PMID: 33242606
Cellular oxidative stress promotes lipid accumulation in macrophages during atherogenesis. Puerarin is a natural isoflavone with beneficial effects against oxidation and atherosclerosis. In this study, we investigated the effects of...
10.
Liu Y, Ou H, Pei X, Jiang B, Ma Y, Liu N, et al.
Curr Med Chem . 2020 Jun; 28(31):6307-6322. PMID: 32503398
Nanoparticles are widely used in cancer therapy because of their nanoscale, high surface ratio, multifunctionality and so on. With specific construction of nanoparticles, by choosing magnetic nanomaterials or citric acid-coated...