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Haihong Huang

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Articles 62
Citations 319
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Recent Articles
1.
Peng C, Luo C, Xiang G, Huang J, Shao L, Huang H, et al.
Animals (Basel) . 2025 Jan; 14(24. PMID: 39765613
The yellowfin seabream () is an economically important commercial mariculture fish in China and Southeast Asia. Only a few simple sequence repeats (SSRs) of have been isolated and reported, which...
2.
Qin B, Wu C, Zhao B, Li G, Wang B, Ou M, et al.
J Med Chem . 2024 Jun; 67(12):10211-10232. PMID: 38871484
Papain-like protease (PLpro) is a promising therapeutic target for its pivotal role in the life cycle of SARS-CoV-2. A series of 1,2,4-oxadiazole derivatives was designed and synthesized via a ring...
3.
Li S, Liao H, Luo L, Meng B, Zheng F, Sheng L, et al.
Eur J Med Chem . 2024 Mar; 269:116327. PMID: 38547733
We report the design and synthesis of a series of proline-derived quinoline formamide compounds as human urate transporter 1 (URAT1) inhibitors via a ligand-based pharmacophore approach. Structure-activity relationship studies reveal...
4.
Qiu L, Wu J, Huang Y, Ye M, Song L, Huang H, et al.
BMJ Open . 2024 Mar; 14(3):e076127. PMID: 38485488
Introduction: Breast cancer-related lymphedema (BCRL) is a common postoperative complication of breast cancer. It develops in a chronic and vicious cycle. Once lymphedema occurs, it cannot be cured and bring...
5.
Ding W, Yan L, Sheng L, Chen S, Li Y, Cheng S, et al.
J Med Chem . 2024 Jan; 67(4):2941-2962. PMID: 38294952
The fibroblast growth factor receptor (FGFR) signaling pathway plays important roles in cellular processes such as proliferation, differentiation, and migration. In this study, we highlighted the potential of FGFR inhibitors...
6.
Cheng S, Zou Y, Chen X, Chen J, Wang B, Tian J, et al.
Eur J Med Chem . 2023 Jun; 258:115571. PMID: 37348296
Mycobacterium tuberculosis infections still pose a serious threat to human health. Combination therapies are effective medical solutions to the problem. Mycobacterium tuberculosis is an intracellular pathogen that mainly depends on...
7.
Huang H, Shi J, Zheng M, Su S, Chen W, Ming J, et al.
Eur Spine J . 2023 May; 32(12):4220-4228. PMID: 37237239
Purpose: The aim is to compare the pathogen detection performance of metagenomic next-generation sequencing (mNGS) and the culturing of percutaneous needle biopsy samples obtained from an individual with a suspected...
8.
Li P, Guo K, Fu L, Wang B, Zhang B, Gong N, et al.
Eur J Med Chem . 2022 Dec; 246:114993. PMID: 36495631
Solubility-driven optimization of the salts of nitro benzothiopyranone 1, which targets DprE1, led to an antimycobacterial preclinical candidate 2. Five pharmaceutically acceptable salts, including the maleate (2), fumarate (3), citrate...
9.
Li P, Wang B, Chen X, Lin Z, Li G, Lu Y, et al.
Bioorg Chem . 2022 Nov; 131:106250. PMID: 36423487
A series of alkynyl-containing maleimides with potent anti-tuberculosis (TB) activity was developed through a rigid group substitution strategy based on our previous study. Systematic optimization of the two side chains...
10.
Liu Y, Huang H, Li L, Jiang W, Liu Z
Environ Sci Pollut Res Int . 2022 Oct; 30(7):18764-18776. PMID: 36219285
Welding is widely used to make assembly of structural components and it will trigger serious environmental pollution, especially waste gas, i.e., carbon dioxide (CO), ozone (O), nitrogen oxide (NO), and...