H Vanden Bossche
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Explore the profile of H Vanden Bossche including associated specialties, affiliations and a list of published articles.
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54
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1168
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Recent Articles
1.
Vanden Bossche H
J Steroid Biochem Mol Biol
. 2012 Jan;
43(8):1003-21.
PMID: 22217845
A number of cytochrome P450-dependent enzymes are major targets for both steroidal and nonsteroidal compounds that may be of use in the treatment of a number of androgen-independent, androgen-, estrogen-...
2.
Odds F, Ausma J, Van Gerven F, Woestenborghs F, Meerpoel L, Heeres J, et al.
Antimicrob Agents Chemother
. 2004 Jan;
48(2):388-91.
PMID: 14742185
R126638 is a new triazole agent with potent antifungal activity in vitro against various dermatophytes, Candida spp., and Malassezia spp. Its activity against Malassezia spp. in vitro was superior to...
3.
Rochette F, Engelen M, Vanden Bossche H
J Vet Pharmacol Ther
. 2003 Feb;
26(1):31-53.
PMID: 12603775
The purpose of this paper is to provide an overview of antifungal agents currently in use in veterinary medicine. The practical applications and the therapeutic regimens that have proved successful...
4.
Vanden Bossche H, Engelen M, Rochette F
J Vet Pharmacol Ther
. 2003 Feb;
26(1):5-29.
PMID: 12603774
A limited number of antifungal agents is licensed for use in animals, however, many of those available for the treatment of mycoses in humans are used by veterinary practitioners. This...
5.
De Backer M, Ilyina T, Ma X, Vandoninck S, Luyten W, Vanden Bossche H
Antimicrob Agents Chemother
. 2001 May;
45(6):1660-70.
PMID: 11353609
The application of genome-wide expression profiling to determine how drugs achieve their therapeutic effect has provided the pharmaceutical industry with an exciting new tool for drug mode-of-action studies. We used...
6.
Stoppie P, Borgers M, Borghgraef P, Dillen L, Goossens J, Sanz G, et al.
J Pharmacol Exp Ther
. 2000 Mar;
293(1):304-12.
PMID: 10734183
All-trans-retinoic acid (RA) regulates epithelial differentiation and growth through activation of specific nuclear RA receptors (RARs). Because high-rate metabolism largely impairs the biological efficacy of RA, we have sought for...
7.
Marichal P, Gorrens J, Laurijssens L, Vermuyten K, Van Hove C, Le Jeune L, et al.
Antimicrob Agents Chemother
. 1999 Oct;
43(11):2663-70.
PMID: 10543744
The effects of itraconazole on ergosterol biosynthesis were investigated in a series of 16 matched clinical Candida albicans isolates which had been previously analyzed for mechanisms of resistance to azoles...
8.
Maesaki S, Marichal P, Vanden Bossche H, Sanglard D, Kohno S
J Antimicrob Chemother
. 1999 Aug;
44(1):27-31.
PMID: 10459807
We investigated the drug efflux mechanism in azole-resistant strains of Candida albicans using rhodamine 6G (R6G). No significant differences in R6G uptake were observed between azole-sensitive B2630 (9.02 +/- 0.02...
9.
Maesaki S, Marichal P, Hossain M, Sanglard D, Vanden Bossche H, Kohno S
J Antimicrob Chemother
. 1999 Mar;
42(6):747-53.
PMID: 10052898
We investigated the effects of combining tacrolimus and azole antifungal agents in azole-resistant strains of Candida albicans by comparing the accumulation of [3H]itraconazole. The CDR1-expressing resistant strain C26 accumulated less...
10.
Vanden Bossche H, Dromer F, Improvisi I, Rex J, Sanglard D
Med Mycol
. 1999 Feb;
36 Suppl 1:119-28.
PMID: 9988500
Failures of drug treatment in fungal infections combined with improvements in performances and standardization of antifungal susceptibility testing have drawn attention to the problem of antifungal resistance and its underlying...