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H van Lenthe

Explore the profile of H van Lenthe including associated specialties, affiliations and a list of published articles. Areas
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Articles 41
Citations 427
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Recent Articles
1.
Potze L, Di Franco S, Grandela C, Pras-Raves M, Picavet D, van Veen H, et al.
Oncogene . 2015 Apr; 35(4):427-37. PMID: 25893306
Cancer is associated with strong changes in lipid metabolism. For instance, normal cells take up fatty acids (FAs) from the circulation, while tumour cells generate their own and become dependent...
2.
de Ruijter J, IJlst L, Kulik W, van Lenthe H, Wagemans T, van Vlies N, et al.
J Inherit Metab Dis . 2012 Sep; 36(2):271-9. PMID: 22968582
Background: Sanfilippo disease (Mucopolysaccharidosis III) is a neurodegenerative lysosomal disorder characterized by accumulation of the glycosaminoglycan heparan sulfate (HS). MPS III has a large phenotypic variability and early assessment of...
3.
Siegelaar S, Kulik W, van Lenthe H, Mukherjee R, Hoekstra J, DeVries J
Diabetes Obes Metab . 2009 Mar; 11(7):709-14. PMID: 19320663
Aim: To assess the effect of three times daily mealtime inhaled insulin therapy compared with once daily basal insulin glargine therapy on 72-h glucose profiles, glucose variability and oxidative stress...
4.
van Kuilenburg A, van Lenthe H, Maring J, van Gennip A
Nucleosides Nucleotides Nucleic Acids . 2006 Oct; 25(9-11):1257-60. PMID: 17065102
In this article, we describe a fast and specific method to measure 5FU with HPLC tandem-mass spectrometry. Reversed-phase HPLC was combined with electrospray ionization tandem mass spectrometry and detection was...
5.
van Kuilenburg A, van Lenthe H, van Gennip A
Nucleosides Nucleotides Nucleic Acids . 2006 Oct; 25(9-11):1211-4. PMID: 17065093
In this study, we measured the activity of dihydropyrimidine dehydrogenase (DPD), dihydropyrimidinase (DHP) and beta-ureidopropionase (beta-UP), using radiolabeled substrates, in 16 different tissues obtained at autopsy from a single patient....
6.
van Kuilenburg A, van Lenthe H, Assmann B, Gohlich-Ratmann G, Hoffmann G, Brautigam C, et al.
J Inherit Metab Dis . 2002 Jan; 24(7):725-32. PMID: 11804209
The pyrimidine bases uracil and thymine are degraded via the consecutive action of three enzymes to beta-alanine and beta-aminoisobutyric acid, respectively. To date, a number of patients have been described...
7.
van Gennip A, van Lenthe H, Ito T, Bootsma A, Van Cruchten A, Wada Y, et al.
Adv Exp Med Biol . 2002 Jan; 486:377-82. PMID: 11783519
No abstract available.
8.
van Kuilenburg A, Haasjes J, van Lenthe H, Zoetekouw L, Waterham H, Vreken P, et al.
Adv Exp Med Biol . 2002 Jan; 486:251-5. PMID: 11783494
No abstract available.
9.
van Kuilenburg A, van Lenthe H, Ratmann G, Assmann B, Hoffmann G, Brautigam C, et al.
Adv Exp Med Biol . 2002 Jan; 486:243-6. PMID: 11783492
No abstract available.
10.
van Kuilenburg A, Haasjes J, Richel D, Zoetekouw L, van Lenthe H, De Abreu R, et al.
Clin Cancer Res . 2001 Jan; 6(12):4705-12. PMID: 11156223
Dihydropyrimidine dehydrogenase (DPD) is the initial and rate-limiting enzyme in the catabolism of 5-fluorouracil (5FU), and it is suggested that patients with a partial deficiency of this enzyme are at...