H R Olpe
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Explore the profile of H R Olpe including associated specialties, affiliations and a list of published articles.
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103
Citations
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Recent Articles
11.
Lingenhohl K, Olpe H, Bendali N, Knopfel T
Neurosci Res
. 1993 Dec;
18(3):229-34.
PMID: 8127471
The interactions of the phenylglycine derivatives (S)-4-carboxyphenylglycine (S-4CPG) and (R,S)-alpha-methyl-4-carboxyphenylglycine (MCPG) with responses of rat cerebellar Purkinje cells to (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD) were examined by intracellular recordings in acute cerebellar...
12.
Lingenhohl K, Knopfel T, Olpe H
Neurosci Res
. 1993 Dec;
18(3):223-8.
PMID: 8127470
The effects of iontophoretically applied (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD), an agonist of metabotropic glutamate receptors, were examined in rat cerebellar Purkinje cells in vivo. Multibarrel electrodes were used for extracellular recordings...
13.
Bittiger H, Froestl W, Mickel S, Olpe H
Trends Pharmacol Sci
. 1993 Nov;
14(11):391-4.
PMID: 7905214
No abstract available.
14.
LEPRE M, Evans R, Olpe H, Brugger F
Neuroscience
. 1993 Aug;
55(3):727-35.
PMID: 7692348
The effects of substance P and the selective neurokinin-1 receptor antagonist (+/-)-CP-96,345 have been compared on in vitro spinal cord preparations from the rat and the gerbil. Substance P produced...
15.
Olpe H, Worner W, Ferrat T
Experientia
. 1993 Jul;
49(6-7):542-6.
PMID: 8392943
Blockade of GABAB receptors was reported to improve cognitive performance in mammals. The physiological basis of this effect is poorly understood. We investigated the effect of the GABAB receptor antagonist...
16.
Brugger F, Wicki U, Olpe H, Froestl W, Mickel S
Eur J Pharmacol
. 1993 Apr;
235(1):153-5.
PMID: 8390938
CGP 52432 (3-N-(3,4-dichlorobenzyl)aminopropyl-P-diethoxymethylphosphinic acid), CGP 54062 (3-N[1-(R,S)-(3,4-dichlorophenyl)ethyl]amino-2-(S)-hydroxypropyl-P-benzy l- phosphinic acid), CGP 54626 (3-N[[1-(S)-(3,4-dichlorophenyl)ethyl]amino-2-(S)- hydroxypropyl-P-cyclohexylmethylphosphinic acid) and CGP 55845 (3-N[1-(S)-(3,4-dichlorophenyl)ethyl]amino-2-(S)- hydroxypropyl-P-benzyl-phosphinic acid) are novel selective GABAB receptor antagonist. The apparent Kd...
17.
Olpe H, Steinmann M, Ferrat T, Pozza M, Greiner K, Brugger F, et al.
Eur J Pharmacol
. 1993 Mar;
233(2-3):179-86.
PMID: 8385620
The goal of this report is to present the results obtained with three new GABAB receptor antagonists. CGP 54062 has an IC50 in a GABAB binding test of 0.013 microM...
18.
Karlsson G, Klebs K, Hafner T, Schmutz M, Olpe H
Experientia
. 1992 Aug;
48(8):748-51.
PMID: 1325369
The aim of this study was to investigate the putative role of GABAB receptors in the development of amygdala kindling in rats. The effects of the GABAB blocker CGP 35348...
19.
Andre P, Ferrat T, Steinman M, Olpe H
Eur J Pharmacol
. 1992 Jul;
218(1):137-43.
PMID: 1327823
The aim of this study was to gain further insight into the function of cortical GABAB receptors. In chloral hydrate-anaesthetized rats, microiontophoretic administration of the GABAB receptor blocker CGP 35348...
20.
Karlsson G, Kolb C, Hausdorf A, Portet C, Schmutz M, Olpe H
Neuroscience
. 1992 Jan;
47(1):63-8.
PMID: 1315938
The effect of the GABAB receptor blocker CGP 35348 on epileptic processes in vitro and in vivo was studied. In hippocampal slices of the rat maintained in vitro, CGP 35348...