H R Kast
Overview
Explore the profile of H R Kast including associated specialties, affiliations and a list of published articles.
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5
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508
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Recent Articles
1.
Kast H, Nguyen C, Sinal C, Jones S, Laffitte B, Reue K, et al.
Mol Endocrinol
. 2001 Oct;
15(10):1720-8.
PMID: 11579204
The farnesoid X-activated receptor (FXR; NR1H4), a member of the nuclear hormone receptor superfamily, induces gene expression in response to several bile acids, including chenodeoxycholic acid. Here we used suppression...
2.
Kast H, Nguyen C, Anisfeld A, Ericsson J, Edwards P
J Lipid Res
. 2001 Aug;
42(8):1266-72.
PMID: 11483628
The CTP:phosphocholine cytidylyltransferase (CT) gene encodes the rate-controlling enzyme in the phosphatidylcholine biosynthesis pathway. CTalpha mRNA levels, like farnesyl diphosphate synthase and the LDL receptor, are repressed when human or...
3.
Laffitte B, REPA J, Joseph S, Wilpitz D, Kast H, Mangelsdorf D, et al.
Proc Natl Acad Sci U S A
. 2001 Jan;
98(2):507-12.
PMID: 11149950
Apolipoprotein E (apoE) secreted by macrophages in the artery wall exerts an important protective effect against the development of atherosclerosis, presumably through its ability to promote lipid efflux. Previous studies...
4.
Edwards P, Tabor D, Kast H, Venkateswaran A
Biochim Biophys Acta
. 2000 Dec;
1529(1-3):103-13.
PMID: 11111080
Sterol regulatory element binding proteins (SREBPs) function as transcription factors that activate specific genes involved in cholesterol synthesis, endocytosis of low density lipoproteins, the synthesis of both saturated and unsaturated...
5.
Laffitte B, Kast H, Nguyen C, Zavacki A, Moore D, Edwards P
J Biol Chem
. 2000 Apr;
275(14):10638-47.
PMID: 10744760
The farnesoid X-activated receptor (FXR; NR1H4) is a member of the nuclear hormone receptor superfamily and functions as a heterodimer with the 9-cis-retinoic acid receptor (RXR). In order to determine...