» Authors » H Lee Sweeney

H Lee Sweeney

Explore the profile of H Lee Sweeney including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 193
Citations 13151
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Carraro U, Alberty M, Anton S, Barbieri E, Bersch I, Blaauw B, et al.
Eur J Transl Myol . 2024 Dec; 34(4). PMID: 39665691
Mega scientific conferences increasingly suffer from the need for short and poster presentations without discussion. An alternative is to organize workshops in hotels large enough to accommodate all participants. This...
2.
Radnai L, Young E, Kikuti C, Hafenbreidel M, Stremel R, Lin L, et al.
bioRxiv . 2024 Oct; PMID: 39416074
Highlights: Research suggests numerous indications, from axon regeneration and cancer, would benefit from a small molecule inhibitor of non-muscle myosin II, a molecular motor that regulates the actin cytoskeleton. Current...
3.
Patsalos A, Halasz L, Oleksak D, Wei X, Nagy G, Tzerpos P, et al.
J Clin Invest . 2024 Aug; 134(20). PMID: 39190487
Tissue regeneration is orchestrated by macrophages that clear damaged cells and promote regenerative inflammation. How macrophages spatially adapt and diversify their functions to support the architectural requirements of actively regenerating...
4.
Gandhi S, Sweeney H, Hart C, Han R, Perry C
Cells . 2024 Jul; 13(14. PMID: 39056750
Duchenne muscular dystrophy (DMD) is a progressive neuromuscular disease caused by mutations to the dystrophin gene, resulting in deficiency of dystrophin protein, loss of myofiber integrity in skeletal and cardiac...
5.
Hart C, Lee Y, Xie J, Gao G, Lin B, Hammers D, et al.
JCI Insight . 2024 May; 9(11). PMID: 38713520
Clinical trials delivering high doses of adeno-associated viruses (AAVs) expressing truncated dystrophin molecules (microdystrophins) are underway for Duchenne muscular dystrophy (DMD). We examined the efficiency and efficacy of this strategy...
6.
Poukalov K, Valero M, Muscato D, Adams L, Chun H, Lee Y, et al.
Proc Natl Acad Sci U S A . 2024 Apr; 121(19):e2321438121. PMID: 38687782
Successful CRISPR/Cas9-based gene editing in skeletal muscle is dependent on efficient propagation of Cas9 to all myonuclei in the myofiber. However, nuclear-targeted gene therapy cargos are strongly restricted to their...
7.
McDonald C, Camino E, Escandon R, Finkel R, Fischer R, Flanigan K, et al.
J Neuromuscul Dis . 2024 Feb; 11(2):499-523. PMID: 38363616
Background: Duchenne muscular dystrophy (DMD) and related dystrophinopathies are neuromuscular conditions with great unmet medical needs that require the development of effective medical treatments. Objective: To aid sponsors in clinical...
8.
Zampieri S, Bersch I, Smeriglio P, Barbieri E, Ganassi M, Leeuwenburg C, et al.
Eur J Transl Myol . 2023 Dec; 33(4). PMID: 38112609
At the end of the 2023 Padua Days of Muscle and Mobility Medicine the next year's meeting was scheduled from 27 February to 2 March 2024 (2024Pdm3). During the summer...
9.
Chen X, Arciola J, Lee Y, Wong P, Yin H, Tao Q, et al.
J Biol Chem . 2023 Dec; 300(1):105523. PMID: 38043799
Filopodia are slender cellular protrusions containing parallel actin bundles involved in environmental sensing and signaling, cell adhesion and migration, and growth cone guidance and extension. Myosin 10 (Myo10), an unconventional...
10.
Hook P, Lee Y, Sweeney H
Biochem Biophys Res Commun . 2023 Dec; 691:149329. PMID: 38042035
The actomyosin cytoskeletal network is responsible for a variety of fundamental cellular processes. Assembly and maintenance of actin networks involve an array of associated regulatory proteins for polymerization, branching, crosslinking...