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H L Fung

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Articles 174
Citations 1236
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Recent Articles
1.
Fung H, Calzada J, Saldana A, Santamaria A, Pineda V, Gonzalez K, et al.
Acta Trop . 2014 Apr; 135:67-74. PMID: 24681221
Dogs play an important role in infectious disease transmission as reservoir hosts of many zoonotic and wildlife pathogens. Nevertheless, unlike wildlife species involved in the life cycle of pathogens, whose...
2.
Yeung C, Cheang C, Lee M, Fung H, Chow W, Ang Jr P
Mar Pollut Bull . 2014 Jan; 85(2):774-82. PMID: 24434001
A recent comprehensive survey covering 125 sites in Hong Kong waters recorded 29 soft coral species in 14 genera, 38 species of gorgonians in 19 genera and six species of...
3.
Kielbasa W, Fung H
AAPS PharmSci . 2001 Dec; 2(2):E11. PMID: 11741227
Our objective was to examine the pharmacokinetic/hemodynamic properties of inhaled isobutyl nitrite (ISBN) in rats. ISBN is one of the volatile organic nitrites that has been used primarily as a...
4.
Maurer T, Fung H
AAPS PharmSci . 2001 Dec; 2(1):E8. PMID: 11741224
The goals of this study were (1) to investigate the performance of 2 classical methods of kinetic analysis when applied to data from enzyme systems in which mechanism-based inactivation and...
5.
Kielbasa W, Fung H
Nitric Oxide . 2001 Dec; 5(6):587-94. PMID: 11730366
Inhaled nitric oxide (iNO) has been shown to reduce pulmonary hypertension associated with several disease states. The effects of iNO are thought to be restricted to the pulmonary vasculature because...
6.
Wang E, Soda D, Fung H
Br J Pharmacol . 2001 Sep; 134(2):418-24. PMID: 11564661
1. Recent studies indicate that nitroglycerin (NTG) can produce beneficial clinical effects in healing anal fissures through the relaxation of the internal anal sphincter. The in vivo relaxation effects of...
7.
Khanna A, Rossman J, Fung H, Caty M
J Surg Res . 2001 Jun; 99(1):114-9. PMID: 11421612
Background: Clinical intestinal ischemia/reperfusion (I/R) injury results in local and systemic dysfunction. A rat model of transient mesenteric occlusion has been used to study this phenomenon. However, a systematic analysis...
8.
Maurer T, Fung H
J Pharm Sci . 2000 Oct; 89(11):1404-14. PMID: 11015686
Mechanism-based enzyme inactivators (MBEIs) have unique kinetic actions that make predictions of potency, selectivity, and potential for metabolic drug interactions more complex than for competitive antagonists. We have derived a...
9.
Kielbasa W, Fung H
Biochem Biophys Res Commun . 2000 Aug; 275(2):335-42. PMID: 10964667
Organic nitrites are nitric oxide (NO) donors that are used predominantly as inhalant drugs of abuse and have been shown to have immunomodulating effects. NO donors can modulate NOS activity...
10.
Maurer T, Fung H
Nitric Oxide . 2000 Aug; 4(4):372-8. PMID: 10944421
The binding affinity (K(I)) and inactivation rate (k(inact)) parameters of nitric oxide synthase (NOS) inhibitors are typically estimated by kinetic activity studies. Methods currently used in the estimation of these...