H K Kleinman
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Explore the profile of H K Kleinman including associated specialties, affiliations and a list of published articles.
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278
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9665
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Recent Articles
1.
Sosne G, Rimmer D, Kleinman H, Ousler G
Vitam Horm
. 2016 Jul;
102:277-306.
PMID: 27450739
Chronic ocular surface diseases such as dry eye, blepharitis, and neurotrophic keratopathies represent a significant and a growing therapeutic challenge. The basis of this expanding prevalence is multifactorial and may...
2.
Kleinman H, Sosne G
Vitam Horm
. 2016 Jul;
102:251-75.
PMID: 27450738
No agent has been identified that significantly accelerates the repair of chronic dermal wounds in humans. Thymosin beta 4 (Tβ4) is a small, abundant, naturally occurring regenerative protein that is...
3.
Almqvist S, Kleinman H, Werthen M, Thomsen P, Agren M
J Wound Care
. 2011 Mar;
20(2):68, 70-5.
PMID: 21378680
Objective: To study the effects of an amelogenin mixture on integrin-dependent adhesion, DNA synthesis and apoptosis of cultured human dermal microvascular endothelial cells and angiogenesis in an organotypic assay. Method:...
4.
Benton G, George J, Kleinman H, Arnaoutova I
J Cell Physiol
. 2009 Jun;
221(1):18-25.
PMID: 19492404
Many cells in tissues are in contact with a highly specialized extracellular matrix, termed the basement membrane. Basement membranes have certain common components, including collagen IV, laminins, heparan sulfate proteoglycans,...
5.
Kleinman H, Cid M
Curr Protoc Cell Biol
. 2008 Jan;
Chapter 2:Unit 2.3.
PMID: 18228348
Endothelial cells, which line blood vessels, can be prepared from a variety of tissues. They are frequently prepared from the umbilical vein, which is relatively easy to obtain. The procedure...
6.
Kleinman H, Jacob K
Curr Protoc Cell Biol
. 2008 Jan;
Chapter 12:Unit 12.2.
PMID: 18228316
Basement membrane is a thin extracellular matrix that underlies epithelia and endothelia and separates them from the stroma. Tumor cells must cross this membrane to invade stroma and establish distant...
7.
Kleinman H
Curr Protoc Cell Biol
. 2008 Jan;
Chapter 10:Unit 10.3.
PMID: 18228297
Gelled substrates can be used for a variety of in vitro and in vivo experiments. A type I collagen gelled substrate will promote cell growth and differentiation. Gelled Matrigel substrate...
8.
Kleinman H
Curr Protoc Cell Biol
. 2008 Jan;
Chapter 10:Unit 10.2.
PMID: 18228296
This unit describes methods for passaging and harvesting the basement membrane matrix-producing EHS tumor and for the subsequent isolation of a crude mixture of basement membrane components termed Matrigel, which...
9.
Lugassy C, Kleinman H, Vernon S, Welch D, Barnhill R
Br J Dermatol
. 2007 Aug;
157(4):780-2.
PMID: 17711523
Background: As distinct from intravascular dissemination, extravascular migratory metastasis (EVMM) has been described as a potential additional mechanism of melanoma spread in which tumour cells migrate along the external surfaces...
10.
Cid M, Hoffman M, Hernandez-Rodriguez J, Segarra M, Elkin M, Sanchez M, et al.
Rheumatology (Oxford)
. 2006 Apr;
45(11):1356-63.
PMID: 16621921
Objective: Patients with giant-cell arteritis (GCA) usually respond dramatically to corticosteroid treatment. However, recurrences are frequent and corticosteroid requirements are highly variable among patients. The aim of our study was...