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H Jeffrey Wilkins

Explore the profile of H Jeffrey Wilkins including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Perlin D, Neil G, Anderson C, Zafir-Lavie I, Raines S, Ware C, et al.
J Clin Invest . 2021 Dec; 132(3). PMID: 34871182
BACKGROUNDSevere coronavirus disease 2019 (COVID-19) is associated with a dysregulated immune response, which can result in cytokine-release syndrome and acute respiratory distress syndrome (ARDS). Patients with COVID-19-associated ARDS have elevated...
2.
Yao H, Najarian K, Gryak J, Bishu S, Rice M, Waljee A, et al.
Gastrointest Endosc . 2020 Aug; 93(3):728-736.e1. PMID: 32810479
Background And Aims: Endoscopy is essential for disease assessment in ulcerative colitis (UC), but subjectivity threatens accuracy and precision. We aimed to pilot a fully automated video analysis system for...
3.
Mahalingam D, Wang J, Hamilton E, Sarantopoulos J, Nemunaitis J, Weems G, et al.
Clin Cancer Res . 2019 Mar; 25(12):3508-3516. PMID: 30819679
Purpose: Transcription factor retinoic acid receptor-related orphan receptor γ (RORγ) regulates type 17 effector T-cell differentiation and function and is key to immune cell regulation. Synthetic RORγ agonists modulate immune...
4.
Spergel J, Rothenberg M, Collins M, Furuta G, Markowitz J, Fuchs 3rd G, et al.
J Allergy Clin Immunol . 2011 Dec; 129(2):456-63, 463.e1-3. PMID: 22206777
Background: Eosinophilic esophagitis is a chronic allergic disease with insufficient treatment options. Results from animal studies suggest that IL-5 induces eosinophil trafficking in the esophagus. Objective: We sought to evaluate...
5.
Castro M, Mathur S, Hargreave F, Boulet L, Xie F, Young J, et al.
Am J Respir Crit Care Med . 2011 Aug; 184(10):1125-32. PMID: 21852542
Rationale: Eosinophilic asthma is a phenotype of asthma characterized by the persistence of eosinophils in the airways. IL-5 is involved in the activation and survival of eosinophils. Objectives: To evaluate...
6.
Porst H, Sharlip I, Hatzichristou D, Rubio-Aurioles E, Gittelman M, Stancil B, et al.
Eur Urol . 2006 Jul; 50(5):1086-94. PMID: 16820261
Objectives: This study explored the efficacy of vardenafil in men with erectile dysfunction (ED) when taken 8 hours before sexual intercourse. Methods: A 10-week, randomized, double-blind, placebo-controlled, parallel-group, flexible-dose study...
7.
Hatzichristou D, Aliotta P, Auerbach S, Barkin J, Lording D, Murdock M, et al.
Clin Ther . 2005 Nov; 27(9):1452-61. PMID: 16291418
Background: The efficacy and tolerability of vardenafil hydrochloride in men with erectile dysfunction (ED) and a history of nonresponse to sildenafil citrate have previously been reported. Objective: The aim of...
8.
Wilkins H, Crane M, Copeland K, Williams W
Am J Hematol . 2005 Sep; 80(2):148-57. PMID: 16184589
Hypereosinophilic syndrome (HES) is a rare disorder that is characterized by persistent and marked eosinophilia combined with organ system dysfunction. HES has substantial clinical heterogeneity but can be fatal without...
9.
Carson C, Hatzichristou D, Carrier S, Lording D, Lyngdorf P, Aliotta P, et al.
BJU Int . 2004 Dec; 94(9):1301-9. PMID: 15610110
Objective: To evaluate the efficacy of vardenafil in patients previously unresponsive to sildenafil. Patients And Methods: A multicentre, double-blind, 12-week, flexible-dose, placebo-controlled trial was conducted, involving 463 men aged >...
10.
Bayliffe A, Brigandi R, Wilkins H, Levick M
Curr Opin Pharmacol . 2004 May; 4(3):306-10. PMID: 15140425
Biopharmaceuticals that target specific disease-mediating molecules have advanced our understanding of the pathogenesis of psoriasis. The traditional paradigm that psoriasis is primarily a disease of epidermal cells has been replaced...