H Hanafusa
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Explore the profile of H Hanafusa including associated specialties, affiliations and a list of published articles.
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277
Citations
9142
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Recent Articles
1.
Sasai K, Kakumoto K, Hanafusa H, Akagi T
Oncogene
. 2006 Jul;
26(3):449-55.
PMID: 16832346
Normal human diploid fibroblasts (HDFs) are refractory to oncogene-mediated transformations in vitro, compared with rodent fibroblasts. As successful oncogene-mediated transformations of normal HDFs have been reported using the human telomerase...
2.
Matsubara N, Yoshitaka T, Hanafusa H, Tanaka N, Shimizu K
J Exp Clin Cancer Res
. 2002 Aug;
21(2):191-5.
PMID: 12148577
Ornithine decarboxylase (ODC), a critical regulatory enzyme for polyamine biosynthesis, is strictly regulated in human cells. Several studies suggested the importance of elevated enzymatic activity and altered biochemical characteristics of...
3.
Yagi R, Ishimaru S, Yano H, Gaul U, Hanafusa H, Sabe H
EMBO Rep
. 2001 Aug;
2(9):814-20.
PMID: 11520860
Paxillin is a protein containing four LIM domains, and functions in integrin signaling. We report here that two transcripts are generated from the paxillin gene locus in Drosophila; one encodes...
4.
Kusakabe M, Masuyama N, Hanafusa H, Nishida E
EMBO Rep
. 2001 Jul;
2(8):727-35.
PMID: 11463744
FRS2 has been identified in mammalian cells as a protein that is tyrosine phosphorylated and binds to Grb2 and Shp2 in response to fibroblast growth factor (FGF) or nerve growth...
5.
Shishido T, Akagi T, Chalmers A, Maeda M, Terada T, Georgescu M, et al.
Genes Cells
. 2001 May;
6(5):431-40.
PMID: 11380621
Background: c-Abl kinase is activated in response to a variety of biological stimuli. Crk family adaptor proteins can interact physically with c-Abl and be involved in the activation of c-Abl...
6.
Hanafusa H, Masuyama N, Kusakabe M, Shibuya H, Nishida E
EMBO Rep
. 2001 Mar;
1(1):32-9.
PMID: 11256621
Although a number of genes that are involved in the establishment of left-right asymmetry have been identified, earlier events in the molecular pathway developing left-right asymmetry remain to be elucidated....
7.
Georgescu M, Kirsch K, Kaloudis P, Yang H, Pavletich N, Hanafusa H
Cancer Res
. 2001 Jan;
60(24):7033-8.
PMID: 11156408
PTEN is a tumor suppressor frequently inactivated in brain, prostate, and uterine cancer. It acts as a phosphoinositide phosphatase and consists of an amino-terminal phosphatase domain tightly linked to a...
8.
Kirsch K, Georgescu M, Shishido T, Langdon W, Birge R, Hanafusa H
J Biol Chem
. 2000 Nov;
276(7):4957-63.
PMID: 11067845
CMS/CD2AP is a cytoplasmic protein critical for the integrity of the kidney glomerular filtration and the T cell function. CMS contains domains and motifs characteristic for protein-protein interactions, and it...
9.
Gunduz M, Ouchida M, Fukushima K, Hanafusa H, Etani T, Nishioka S, et al.
Cancer Res
. 2000 Jun;
60(12):3143-6.
PMID: 10866301
We characterized the genomic structure of the human ING1 gene, a candidate tumor suppressor gene, and found that the gene has three exons. We also demonstrated that four mRNA variants...
10.
Ichimura K, Hanafusa H, Takimoto H, Ohgama Y, Akagi T, Shimizu K
Gene
. 2000 Jun;
251(1):37-43.
PMID: 10863094
The human p107 protein shares many structural and functional features with the retinoblastoma gene product and retinoblastoma-related p130 protein. In this study, we have cloned and elucidated the complete intron-exon...