E A GARBER
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Explore the profile of E A GARBER including associated specialties, affiliations and a list of published articles.
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53
Citations
1767
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Recent Articles
1.
Kohtz J, Lee H, Gaiano N, Segal J, Ng E, Larson T, et al.
Development
. 2001 Aug;
128(12):2351-63.
PMID: 11493554
The adult basal ganglia arise from the medial and lateral ganglionic eminences, morphologically distinct structures found in the embryonic telencephalon. We have previously shown that temporal changes in sonic hedgehog...
2.
Pathi S, Baker D, GARBER E, Rayhorn P, Bumcrot D, Tabin C, et al.
Mech Dev
. 2001 Jul;
106(1-2):107-17.
PMID: 11472839
A comprehensive comparison of Sonic (Shh), Indian (Ihh), and Desert (Dhh) hedgehog biological activities has not previously been undertaken. To test whether the three higher vertebrate Hh proteins have distinct...
3.
Taylor F, Wen D, GARBER E, Carmillo A, Baker D, Arduini R, et al.
Biochemistry
. 2001 Apr;
40(14):4359-71.
PMID: 11284692
Post-translational modifications of the developmental signaling protein Sonic hedgehog (Shh) by a long-chain fatty acid at the N-terminus and cholesterol at the C-terminus greatly activate the protein in a cell-based...
4.
Pepinsky R, Rayhorn P, Day E, Dergay A, Williams K, Galdes A, et al.
J Biol Chem
. 2001 Feb;
275(15):10995-1001.
PMID: 10753901
We have defined regions in the Sonic hedgehog (Shh) molecule that are important for Patched (Ptc) receptor binding by targeting selected surface amino acid residues with probes of diverse sizes...
5.
Su L, GARBER E, Hsu Y
J Biol Chem
. 2000 Nov;
276(3):1673-6.
PMID: 11073939
X-linked hyper-IgM (XHIM) syndrome is an immunological disorder resulting from mutations in the CD154 gene. Some mutations occur in splicing sites and result in transcripts encoding wild-type and mutant proteins....
6.
Emanuel P, Dang J, Gebhardt J, Aldrich J, GARBER E, Kulaga H, et al.
Biosens Bioelectron
. 2000 Aug;
14(10-11):751-9.
PMID: 10945449
Antibodies are critical reagents used in several biodetection platforms for the identification of biological agents. Recent advances in phage display technology allow isolation of high affinity recombinant antibody fragments (Fabs)...
7.
Wang L, Liu Z, Gambardella L, Delacour A, Shapiro R, Yang J, et al.
J Invest Dermatol
. 2000 Apr;
114(5):901-8.
PMID: 10771469
Members of the vertebrate hedgehog family (Sonic, Indian, and Desert) have been shown to be essential for the development of various organ systems, including neural, somite, limb, skeletal, and for...
8.
Williams K, Rayhorn P, GARBER E, Strauch K, Horan G, Reilly J, et al.
J Cell Sci
. 1999 Nov;
112 ( Pt 23):4405-14.
PMID: 10564658
During development, sonic hedgehog functions as a morphogen in both a short-range contact-dependent and in a long-range diffusable mode. Here, we show using a panel of sonic hedgehog variants that...
9.
Day E, Wen D, GARBER E, Hong J, Avedissian L, Rayhorn P, et al.
Biochemistry
. 1999 Nov;
38(45):14868-80.
PMID: 10555969
The role of the zinc site in the N-terminal fragment of human Sonic hedgehog (ShhN) was explored by comparing the biophysical and functional properties of wild-type ShhN with those of...
10.
Pepinsky R, Zeng C, Wen D, Rayhorn P, Baker D, Williams K, et al.
J Biol Chem
. 1998 Jun;
273(22):14037-45.
PMID: 9593755
During hedgehog biosynthesis, autocatalytic processing produces a lipid-modified amino-terminal fragment (residues 24-197 in the human Sonic hedgehog sequence) that is responsible for all known hedgehog signaling activity and that is...