H A Hahm
Overview
Explore the profile of H A Hahm including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
94
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Recent Articles
1.
Hahm H, Dunn V, Butash K, Deveraux W, Woster P, Casero Jr R, et al.
Clin Cancer Res
. 2001 Mar;
7(2):391-9.
PMID: 11234895
Polyamines are essential for cell growth and differentiation. Structural polyamine analogues have been shown to have antitumor activity in experimental models including breast cancer. The ability of polyamine analogues to...
2.
Jackisch C, Hahm H, Tombal B, McCloskey D, Butash K, Davidson N, et al.
Clin Cancer Res
. 2000 Jul;
6(7):2844-50.
PMID: 10914733
Thapsigargin (TG), a highly specific inhibitor of the sarcoplasmic reticulum and endoplasmic reticulum Ca2+-ATPase pump, can induce apoptosis in a variety of epithelial and lymphoid cell types. In prostate cancer...
3.
Hahm H, Armstrong D, Chen T, Grochow L, Goodman S, Davidson N, et al.
Biol Blood Marrow Transplant
. 2000 Jul;
6(3A):335-43.
PMID: 10905771
We conducted the first phase 2 and pharmacologic study to evaluate the combination of novobiocin (a coumeromycin antibiotic that has been shown to augment alkylating agent cytotoxicity in experimental models)...
4.
Clinical aspects of cell death in breast cancer: the polyamine pathway as a new target for treatment
Davidson N, Hahm H, McCloskey D, Woster P, Casero Jr R
Endocr Relat Cancer
. 2000 Mar;
6(1):69-73.
PMID: 10732790
Because intracellular polyamines have a critical role in cell proliferation and death pathways, the polyamine metabolic pathway represents a potential target for intervention in cancers. A number of polyamine analogues...
5.
6.
Hahm H, Davidson N, Giguere J, DiBernardo C, OReilly S
J Clin Oncol
. 1998 Jun;
16(6):2280-2.
PMID: 9626232
No abstract available.
7.
Denmeade S, McCloskey D, Joseph I, Hahm H, Isaacs J, Davidson N
Adv Pharmacol
. 1997 Jan;
41:553-83.
PMID: 9204159
No abstract available.
8.
Davidson N, Prestigiacomo L, Hahm H
Cancer Res
. 1993 Jan;
53(2):291-7.
PMID: 8417822
To investigate whether estrogen treatment of hormone-responsive human breast cancer cells was associated with activation of members of the jun family of immediate early response genes, the expression of these...
9.
Darcy K, Black J, Hahm H, Ip M
Exp Cell Res
. 1991 Sep;
196(1):49-65.
PMID: 1879471
We have recently described a primary culture system which allows for extensive proliferation and functional differentiation of immature mammary epithelial cells. Herein, these findings are extended to demonstrate that a...
10.
Hahm H, Ip M, DArcy K, Black J, Shea W, Forczek S, et al.
In Vitro Cell Dev Biol
. 1990 Aug;
26(8):803-14.
PMID: 2394675
A serum-free primary culture system is described which allows normal rat mammary epithelial cells (RMECs) embedded within a reconstituted basement membrane to undergo extensive growth and functional differentiation as detected...