H A Giebler
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Explore the profile of H A Giebler including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
407
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Recent Articles
1.
Giebler H, Lemasson I, Nyborg J
Mol Cell Biol
. 2000 Jun;
20(13):4849-58.
PMID: 10848610
CREB binding protein (CBP) is a 270-kDa nuclear protein required for activated transcription of a large number of cellular genes. Although CBP was originally discovered through its interaction with phosphorylated...
2.
Van Orden K, Giebler H, Lemasson I, Gonzales M, Nyborg J
J Biol Chem
. 1999 Sep;
274(37):26321-8.
PMID: 10473588
The pleiotropic cellular coactivator CREB binding protein (CBP) plays a critical role in supporting p53-dependent tumor suppressor functions. p53 has been shown to directly interact with a carboxyl-terminal region of...
3.
Yan J, Garrus J, Giebler H, Stargell L, Nyborg J
J Mol Biol
. 1998 Aug;
281(3):395-400.
PMID: 9698555
The oncoprotein Tax, encoded by the human T-cell leukemia virus type I (HTLV-I), is required for high-level viral transcription and is strongly linked to HTLV-I-associated malignant transformation. Recent evidence suggests...
4.
Lenzmeier B, Giebler H, Nyborg J
Mol Cell Biol
. 1998 Feb;
18(2):721-31.
PMID: 9447968
Efficient human T-cell leukemia virus type 1 (HTLV-1) replication and viral gene expression are dependent upon the virally encoded oncoprotein Tax. To activate HTLV-1 transcription, Tax interacts with the cellular...
5.
Giebler H, Loring J, Van Orden K, Colgin M, Garrus J, Escudero K, et al.
Mol Cell Biol
. 1997 Sep;
17(9):5156-64.
PMID: 9271393
The human T-cell leukemia virus type 1 (HTLV-1)-encoded Tax protein activates viral transcription through interaction with the cellular transcription factor CREB (cyclic AMP response element [CRE] binding protein). Although Tax...
6.
Uittenbogaard M, Giebler H, Reisman D, Nyborg J
J Biol Chem
. 1995 Dec;
270(48):28503-6.
PMID: 7499359
The human T-cell leukemia virus type I oncoprotein Tax transcriptionally deregulates a wide variety of viral and cellular genes. Tax deregulation of gene expression is mediated through interaction with a...
7.
Baranger A, Palmer C, Hamm M, Giebler H, Brauweiler A, Nyborg J, et al.
Nature
. 1995 Aug;
376(6541):606-8.
PMID: 7637812
Tax protein activates transcription of the human T-cell leukaemia virus type I (HTLV-I) genome through three imperfect cyclic AMP-responsive element (CRE) target sites located within the viral promoter. Previous work...
8.
Brauweiler A, Garl P, Franklin A, Giebler H, Nyborg J
J Biol Chem
. 1995 May;
270(21):12814-22.
PMID: 7759537
The human T-cell leukemia virus type I (HTLV-I) is the causative agent of an aggressive T-cell malignancy in humans. While the virus appears to maintain a state of latency in...
9.
Armstrong A, Franklin A, Uittenbogaard M, Giebler H, Nyborg J
Proc Natl Acad Sci U S A
. 1993 Aug;
90(15):7303-7.
PMID: 8346248
The Tax protein, encoded by the human T-cell leukemia virus type I, is a potent activator of viral and cellular gene transcription. Tax does not bind DNA directly but appears...