Guy Poirier
Overview
Explore the profile of Guy Poirier including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
350
Followers
0
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Recent Articles
1.
OSullivan J, Mersaoui S, Poirier G, Masson J
J Vis Exp
. 2021 May;
(170).
PMID: 33999036
The study of the DNA damage response (DDR) is a complex and essential field, which has only become more important due to the use of DDR-targeting drugs for cancer treatment....
2.
Melki I, Allaeys I, Tessandier N, Levesque T, Cloutier N, Laroche A, et al.
Sci Transl Med
. 2021 Feb;
13(581).
PMID: 33597264
The accumulation of DNA and nuclear components in blood and their recognition by autoantibodies play a central role in the pathophysiology of systemic lupus erythematosus (SLE). Despite the efforts, the...
3.
Cloutier N, Allaeys I, Marcoux G, Machlus K, Mailhot B, Zufferey A, et al.
Proc Natl Acad Sci U S A
. 2018 Feb;
115(7):E1550-E1559.
PMID: 29386381
There is a growing appreciation for the contribution of platelets to immunity; however, our knowledge mostly relies on platelet functions associated with vascular injury and the prevention of bleeding. Circulating...
4.
Cieslak A, Kelly I, Trottier J, Verreault M, Wunsch E, Milkiewicz P, et al.
Proteomics
. 2016 Sep;
16(21):2827-2837.
PMID: 27634100
This study aimed at establishing a sensitive multiple reaction monitoring-mass spectrometry (MRM-MS) method for the quantification of the drug metabolizing cytochrome P450 (CYP)3A4 enzyme in human liver homogenates. Liver samples...
5.
Rodrigue A, Coulombe Y, Jacquet K, Gagne J, Roques C, Gobeil S, et al.
J Cell Sci
. 2012 Oct;
126(Pt 1):348-59.
PMID: 23108668
The interplay between homologous DNA recombination and mitotic progression is poorly understood. The five RAD51 paralogs (RAD51B, RAD51C, RAD51D, XRCC2 and XRCC3) are key enzymes for DNA double-strand break repair....
6.
Rulten S, Fisher A, Robert I, Zuma M, Rouleau M, Ju L, et al.
Mol Cell
. 2011 Jan;
41(1):33-45.
PMID: 21211721
PARP-3 is a member of the ADP-ribosyl transferase superfamily of unknown function. We show that PARP-3 is stimulated by DNA double-strand breaks (DSBs) in vitro and functions in the same...