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Guy Nadel

Explore the profile of Guy Nadel including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Nadel G, Yao Z, Hacohen-Lev-Ran A, Wainstein E, Maik-Rachline G, Ziv T, et al.
Cell Commun Signal . 2024 Feb; 22(1):154. PMID: 38419089
Background: Although GqPCR activation often leads to cell survival by activating the PI3K/AKT pathway, it was previously shown that in several cell types AKT activity is reduced and leads to...
2.
Nadel G, Maik-Rachline G, Seger R
Int J Mol Sci . 2023 Sep; 24(17). PMID: 37686335
The response of cells to extracellular signals is mediated by a variety of intracellular signaling pathways that determine stimulus-dependent cell fates. One such pathway is the cJun-N-terminal Kinase (JNK) cascade,...
3.
Nadel G, Yao Z, Wainstein E, Cohen I, Ben-Ami I, Schajnovitz A, et al.
Cell Commun Signal . 2022 Jan; 20(1):5. PMID: 34998390
Background: G protein-coupled receptors (GPCRs) usually regulate cellular processes via activation of intracellular signaling pathways. However, we have previously shown that in several cell lines, GqPCRs induce immediate inactivation of...
4.
Nadel G, Yao Z, Ben-Ami I, Naor Z, Seger R
Cell Physiol Biochem . 2018 Oct; 50(1):121-135. PMID: 30278445
Background/aims: Gq protein-coupled receptors (GqPCRs) regulate various cellular processes including mainly proliferation and differentiation. In a previous study, we found that in prostate cancer cells, the GqPCR of GnRH induces...
5.
Mitrani E, Nadel G, Hasson E, Harari E, Shimoni Y
Differentiation . 2005 Apr; 73(2-3):79-87. PMID: 15811131
We here report that preservation of the basic epithelial-mesenchymal interactions allows for highly complex ex vivo function of epidermal cells. The approach taken is based on the preparation of organ...